Mutations were introduced into conserved steroidogenic factor 1 (SF1)- and SOX9-binding sites within the endogenous mouse Mullerian inhibiting substance (Mis) promoter. Male mice homozygous for the mutant SF1-binding site correctly initiated Mis transcription in fetal testes, although at significantly reduced levels. Surprisingly, sufficient MIS was produced to eliminate the MUllerian ducts. In...

It is acknowledged that MIS knowledge has always resided in conceptualizing and developing applications in the context of ‘explicit’ and well defined knowledge. In this paper, however, we contend that the less tangible aspect of knowledge, ‘tacit’ knowledge, is now the area that demands more attention from MIS researchers and academics. Tacit knowledge provides the organizational context for MI...

BACKGROUND Previous studies reported that the mild hypothermia therapy (MHT) could significantly improve the clinical outcomes for patients with hypertensive intracerebral hemorrhage (HICH). Therefore, this meta-analysis was conducted to systematically assess whether the addition of local MHT (LMHT) could significantly improve the efficacy of minimally invasive surgery (MIS) in treating HICH. ...

We describe the molecular cloning and characterization of a novel myeloid inhibitory siglec, MIS, that belongs to the family of sialic acid-binding immunoglobulin-like lectins. A full-length MIS cDNA was obtained from murine bone marrow cells. MIS is predicted to contain an extracellular region comprising three immunoglobulin-like domains (V-set amino-terminal domain followed by two C-set domai...

This study investigates the effects of rotor magnetic isolation dimensions on no-load performance ultra-low speed high torque spoke type permanent magnet motor. The studied motor structures are shown, where parts include a barrier near air gap (MB-NAG), sleeve (MB-NMIS), (MIS). circuit model is performed and finite element analysis method used to analyse performance. Through analysing with thre...

BACKGROUND The goal of this editorial and literature review is to define the term "minimally invasive surgery" (MIS) as it relates to the spine and characterize methods of measuring parameters of a spine MIS technique. METHODS This report is an analysis of 105,845 cases of spinal surgery in unmatched series and 95,161 cases in paired series of open compared with MIS procedures performed by th...

OBJECTIVE To validate the Motor Impairment Scale (MIS) of the Korean long-term care insurance (LTCI) system by comparing with the service time offered for aiding activities of daily living (ADL) and the ADL score. METHODS A total of 407 elderly subjects without dementia who had used LTCI services were included in this study. Spearman correlations and multivariate linear regression models were...

When comparing the present situations of the Management Information Systems (MIS) undergraduate program in Shanghai Jiao Tong University with several representative domestic MIS programs in other universities, the authors discover there exist three different types of training objectives in MIS education in China. We also conclude that the MIS education in the top 4 MIS undergraduate programs in...

Müllerian inhibiting substance (MIS), also called anti-Müllerian hormone (AMH), is a member of the transforming growth factor-β super-family of growth and differentiation response modifiers. It is produced in immature Sertoli cells in male embryos and binds to MIS/AMH receptors in primordial Müllerian ducts to cause regression of female reproductive structures that are the precursors to the fal...