Introduction: Body mass index (BMI) can affect cardiac morphology; however, the relationship between BMI and valvular heart diseases has not been thoroughly evaluated. This study aimed to determine the relationship between BMI and mitral valve prolapse (MVP) as one of the most common valve diseases worldwide. It can help us to better understand pathophysiology of this common disease. Materials ...

OBJECTIVE We aimed to investigate the association of diffuse myocardial fibrosis by cardiac magnetic resonance (CMR) T1 with complex ventricular arrhythmia (ComVA) in mitral valve prolapse (MVP). METHODS A retrospective analysis was performed on 41 consecutive patients with MVP referred for CMR between 2006 and 2011, and 31 healthy controls. Arrhythmia analysis was available in 23 patients wi...

BACKGROUND Celiac artery stenosis (CAS) may be caused by atherosclerotic degeneration or compression exerted by the arched ligament of the diaphragm. Mitral valve prolapse (MVP) is the most common valvular disorder. There are no reports on an association between CAS and MVP. METHODS 1560 (41%) out of 3780 consecutive patients undergoing echocardiographic assessment of MVP, had Doppler sonogra...

BACKGROUND This study was undertaken to compare mitral valve repair and replacement as treatments for ischemic mitral regurgitation (IMR) with left ventricular dysfunction (LVD). Specifically, we sought to determine whether the choice of mitral valve procedure affected survival, and discover which patients were predicted to benefit from mitral valve repair and which from replacement. METHODS ...

Background. Mitral valve prolapse (MVP) is the most common cause of severe mitral regurgitation. Besides echocardiography, up to now there are no reliable biomarkers available for the identification of this pathology. We aim to generate a predictive model, based on circulating biomarkers, able to identify MVP patients with the highest accuracy. Methods. We analysed 43 patients who underwent mit...

Abstract Background Mitral valve prolapse (MVP) is a well-known pro-arrhythmic condition that involves 2-3% of the general population with an incidence nonfatal arrhythmic events up to 30% and sudden cardiac death 2-4% per year. It assumed substrate consists in myocardial fibrosis, secondary steer-stretch due anomalous mobility mitral apparatus. We still have gaps evidences about risk stratific...

Mitral valve prolapse (MVP) and mild mitral regurgitation (MR) are ones of the most common structural changes heart affect many young individuals, who aspire to partake in competitive sport or high intensity recreational exercise. These two conditions associated with a different prognosis possible omplications such as failure (HF), malignant arrhythmias sudden cardiac death (SCD). Therefore it ...

Patients with mitral valve prolapse (MVP) frequently experience chest pain which may, expecially in older subjects and males, be difficult to differentiate from angina pectoris. Electrocardiographic (ECG) changes, ventricular arrhythmias, metabolic abnormalities and rare reports of myocardial infarction and sudden death further suggest the presence of an ischemic process in these patients. The ...

Background Recently, basal left ventricular hypertrophy has been suggested as a new form of hypertrophic cardiomyopathy. However, we have noticed that substantial focal basal hypertrophy often occurs in patients with mitral valve prolapse (Figure 1). Our objective was to characterize the extent and distribution of focal basal left ventricular hypertrophy in patients with MVP and assess the corr...