Luminescent metal–organic frameworks (MOFs) have received much attention due to their wide structural tunability and potential application in light-emitting diodes, biological imaging and chemical sensors. However, successful examples of long-persistent afterglow MOFs are still quite limited to date. In this work, we report that two types of Zn-terephthalate (TPA) MOFs (namely [Zn(TPA)(DMF)] (1...

Li adsorption on isoreticular MOFs with metal Fe, Cu, Co, Ni and Zn was studied using density function theory. Li functionalization shows a considerable structural change associated with a volume change in isoreticular MOF-5 except for the Zn metal center. Hydrogen binding energies on Li functionalized MOFs are seen to be in the range of 0.2 eV, which is the desired value for an ideal reversibl...

Several randomized trials have shown superior response rates for 5-fluorouracil (5-FU) combined with folinic acid as compared to 5-FU alone. Both treatment regimens are well tolerated and generally can be applied in an outpatient setting. To date no other tested drug combination as methyl-CCNU (M), vincristine (O) and 5-FU (MOF), cisplatin and 5-FU (DDP/5-FU) or methotrexate and 5-FU (MTX/5-FU)...

The assembly of components from solution into the solid state can be accomplished in numerous manners, and each of these pathways can give rise to unique materials. The effects of the assembly pathway can be relatively subtle, as in the crystallization of pharmaceuticals into polymorphic crystals, or more dramatic, involving changes in strong bonding, as is often encountered in the preparation ...

BACKGROUND Cardiovascular diseases are expanding to a major social-economic burden in the Western World and undermine man's deep desire for healthy ageing. Epidemiological studies suggest that flavanol-rich foods (e.g. grapes, wine, chocolate) sustain cardiovascular health. For an evidenced-based application, however, sound clinical data on their efficacy are strongly demanded. METHODS In a d...

Three Keggin-based metal-organic frameworks (MOFs) containing multi-nuclear silver subunits, [Ag7(ptz)5(H2O)2][H2SiMo12O40] (1), [Ag8(ptz)5(H2O)2][AsW12O40] (2) and [Ag7(ptz)5(H2O)][HAsMo12O40] (3) (ptzH = 5-(4-pyridyl)-tetrazole), have been synthesized under hydrothermal conditions by changing the inorganic polyanions. The new compounds have been characterized by elemental analyses, TG analyse...

A series of metallosalen-based metal-organic frameworks (MOFs) have been prepared by the post-synthesis modification of Mn(III)SO-MOF, a Mn(3+)(salen)-based MOF. Treatment of Mn(III)SO-MOF with H(2)O(2) effects the removal of the Mn(3+) ions from the salen struts, which can then be remetalated with a variety of metal precursors to form isostructural MSO-MOF materials. The presence of the new me...

HYPOTHESIS The incidence and severity of postinjury multiple organ failure (MOF) has decreased over the last decade. DESIGN A prospective 12-year inception cohort study ending December 31, 2003. SETTING Regional academic level I trauma center. PATIENTS One thousand three hundred forty-four trauma patients at risk for postinjury MOF. Inclusion criteria were aged older than 15 years, admiss...

The activity and recyclability of Cu-MOF-74 as a catalyst was studied for the ligand-free C-O cross-coupling reaction of 4-nitrobenzaldehyde (NB) with phenol (Ph) to form 4-formyldiphenyl ether (FDE). Cu-MOF-74 is characterized by having unsaturated copper sites in a highly porous metal-organic framework. The influence of solvent, reaction temperature, NB/Ph ratio, catalyst concentration, and b...

Despite its high refractive index sensitivity, localized surface plasmon resonance (LSPR) spectroscopy has been generally restricted to large biological analytes. Sensing of smaller molecules is a compelling target for this technique; in particular, LSPR spectroscopy could be utilized to detect hazardous or toxic gases and manage industrial processes involving gaseous chemicals. Here, we report...