The formation of imprinted memories during a critical period is crucial for vital behaviors, including filial attachment. Yet, little is known about the underlying molecular mechanisms. Using a combination of behavior, pharmacology, in vivo surface sensing of translation (SUnSET) and DiOlistic labeling we found that, translational control by the eukaryotic translation initiation factor 2 alpha ...

T h e term genomic imprinting has been used to refer to all cases where genes have differential expression depending on the sex of the parent from which they are inherited~-3. At least two distinct phenomena have been described as imprinting and it is important to distinguish between them. In fungus gnats (Sciaridae), gall midges (Cecidomyidae) and scale insects (Coccoidea), the paternal set of...

Engineering the molecular design of intelligent biomaterials by controlling recognition and specificity is the first step in coordinating and duplicating complex biological and physiological processes. We address design and synthesis characteristics of artificial molecular structures capable of specific molecular recognition of biological molecules. Recent developments in protein delivery have ...

Introduction The organizers of the European Molecular Biology Organization Workshop on Genomic Imprinting chose a truly trans-kingdom selection of speakers; there was a strong representation of those working in plants and mammals, with a sprinkling of those studying flies and worms. This organismal diversity was layered further with talks on topics ranging from germ cells, genomic imprinting an...