INTRODUCTION A ccording to 2007 data from the National Institute of Diabetes and Digestive and Kidney Diseases, 23.6 million people—7.8% of the US population have diabetes (1). Also, diabetes incurred an estimated expenditure of $174 billion in direct and indirect costs in 2007 (1). Part of this cost (estimated to be $22.9 billion in 2006) can be attributed to the treatment of diabetes-related ...

BACKGROUND Gastrointestinal (GI) symptoms are common in patients with eating disorders. The aim of this study was to determine, using factor analysis, whether these GI symptom factors (clusters) in eating disorder patients hold true to the Rome II classification of functional gastrointestinal disorders (FGIDs). METHODS Inpatients in a specialised eating disorder unit completed the Rome II que...

Autism spectrum disorder (ASD) affects a significant number of individuals worldwide with the prevalence continuing to grow. It is becoming clear that a large subgroup of individuals with ASD demonstrate abnormalities in mitochondrial function as well as gastrointestinal (GI) symptoms. Interestingly, GI disturbances are common in individuals with mitochondrial disorders and have been reported t...

Mechanical ventilation (MV) can be lifesaving by maintaining gas exchange until the underlying disorders are corrected, but it is associated with numerous organ-system complications, which can significantly affect the outcome of critically ill patients. Like other organ systems, GI complications may be directly attributable to MV, but most are a reflection of the severity of the underlying dise...

background this study aimed to determine the common etiologies and character­istics of lower gastrointestinal (gi) bleeding in children from southern iran. methods this five-year prospective cross-sectional study was performed from march 2006 to march 2011 in nemazee hospital. all pediatric patients (<18 years of age) who referred to our center with visible lower gi bleed­ing or two consecutive...

Anxiety-related concerns are among the most common presenting problems for schoolage children and adolescents with autism spectrum disorder (ASD) in clinical settings. The current study examined the relationship between anxiety and gastrointestinal (GI) symptoms, sleep problems, and challenging behavior in a sample of children and adolescents with ASD, aged 6–17 years. Parental measures were co...

BACKGROUND Gastrointestinal complaints are very common in the general population and very often co-occur with common mental disorders. We aimed to study the prospective impact of gastrointestinal complaints on long term sickness absence, and address the contribution from co-occurring common mental disorders and other somatic symptoms. METHOD Health data on 13 880 40-45 year olds from the Hord...

Anxiety-related concerns are among the most common presenting problems for school-age children and adolescents with autism spectrum disorder (ASD) in clinical settings. The current study examined the relationship between anxiety and gastrointestinal (GI) symptoms, sleep problems, and challenging behavior in a sample of children and adolescents with ASD, aged 6-17 years. Parental measures were c...

Recent studies suggest a role for the microbiota in autism spectrum disorders (ASD), potentially arising from their role in modulating the immune system and gastrointestinal (GI) function or from gut-brain interactions dependent or independent from the immune system. GI problems such as chronic constipation and/or diarrhea are common in children with ASD, and significantly worsen their behavior...

A recent editorial in the journal commented that: based on their prevalence and health-economic impact, disorders of gastrointestinal (GI) motor and sensory function continue to represent a major unmet need . Although all investigators working in this field would likely concur with the statement, it is important that we are clear in our minds what conditions these disorders actually represent, ...