The Hedgehog (Hh) signaling pathway has critical functions during embryogenesis of both invertebrate and vertebrate species [1]; defects in this pathway in humans can cause developmental disorders as well as neoplasia [2]. Although the Gli1, Gli2, and Gli3 zinc finger proteins are known to be effectors of Hh signaling in vertebrates, the mechanisms regulating activity of these transcription fac...

Satellite-based layer average stratospheric temperature (T) climate data records (CDRs) now span more than three decades and so can elucidate climate variability associated with processes on multiple time scales. We intercompare and analyze available published T CDRs covering at least two decades, with a focus on Stratospheric Sounding Unit (SSU) and Microwave Sounding Unit (MSU) CDRs. Recent r...

Welcome to Michigan State University. It is our hope that your life at MSU will be fulfilling and successful, now and in the future. To enable you to begin the process of learning the lay of the land at MSU, we have created this orientation website designed specifically for new Fixed Term Faculty. We invite you to explore this website carefully. It provides information on relevant orientation e...

Michigan State University Quality Matters: Teaching Tools MSU has a campus subscription to QM. This page provides information for creating a personal QM account in order to make full use of the QM rubric and online resources to create and assess improved online education and student learning. Also offers links to other technology tools for teaching available at MSU. https://tech.msu.edu/teachin...

Monosodium urate (MSU), calcium pyrophosphate dihydrate (CPPD) and basic calcium phosphate (BCP) crystals deposit in joints and surrounding tissues causing acute inflammation and chronic cartilage damage. A number of endogenous substances and physicochemical conditions affect their precipitation, growth and even dissolution, regulating their metabolism and inflammatory activity. We review how M...

BACKGROUND The American Heart Association Position Statement on Cardiovascular Health Promotion in Public Schools encourages school-based interventions for the primary prevention of cardiovascular disease (CVD) through risk factor prevention or reduction in children with an emphasis on creating an environment that promotes healthy food choices and physical activity (PA). In an effort to address...

A newly identified locus in Drosophila melanogaster, Mosaic suppressor (Msu), is described. This gene modifies the expression of white-apricot (wa), which is a copia retrotransposon-induced allele of the white gene. In addition to suppressing wa in a mosaic fashion, this mutation suppresses or enhances the expression of several other retrotransposon induced white alleles. Mutations in Msu alter...

The College of Nursing (CON), Michigan State University (MSU), in collaboration with the School of Nursing and Obstetrics, University of Guanajuato, Celaya, Mexico, developed a semester-long study-abroad program for senior MSU nursing students offered for the first time in the fall of 1998. The program provides intensive Spanish language classes and allows students to take required nursing cour...

A lipase producing bacterium, Bacillus cereus MSU AS was isolated from the gut of a marine fish Sardinella longiceps. In total, seven agricultural waste substrates (coconut oil cake, neem oil cake, onion skin waste, wheat bran, jack fruit waste, banana skin peels and pomegranate skin peel) were selected for solid state production of lipase by B. cereus MSU AS. Among the tested substrates, onion...