Condyloma acuminatum, is a rare sexually transmitted disease. The virus responsible for condyloma is human papillomavirus. HPV-6 and HPV-11 are the most commonly detected HPV genotypes, but at least 20 other HPV genotypes have occasionally been found in genital wart tissue specimens. In fact genital HPV infection is common among sexually active populations. This disease may occur at any age af...

The advent of anti-tumor necrosis factor (TNF) therapies revolutionized the treatment of inflammatory bowel disease. Adalimumab is a subcutaneous anti-TNF agent indicated for use in patients with moderate-to-severe Crohn's disease and those with moderate-to-severe ulcerative colitis. In both diseases, it can be used for both induction of remission and for maintenance of remission. This review f...

BACKGROUND Gastroesophageal reflux disease is an increasingly common condition worldwide causing a considerable economic impact. More than half the patients with clinical symptoms of reflux disease display no mucosal erosions on esophagogastroduodenoscopy, making it impossible to confirm the diagnosis without further investigations. AIM To evaluate the correlation between minimal endoscopic c...

The current situation of bovine virus diarrhoea-mucosal disease (BVD-MD) virus infections is briefly reviewed, with special reference to problems arising from fetal infection in the Hokkaido district, a northern island of Japan. The results of some investigations on BVD-MD virus carried out in Japan are also described. Although bovine congenital anomalies caused by BVD-MD virus and mucosal dise...

The mucosal surfaces are constantly exposed to incoming pathogens which can cause infections that result in severe morbidity and/or mortality. Studies have reported that mucosal immunity is important for providing protection against these pathogens and that mucosal vaccination is effective in preventing local infections. For many years, the sublingual mucosa has been targeted to deliver immunot...

Coccidiosis and gizzard erosion are rare conditions in cage bird. A male zebra finch was presented with a history of watery diarrhea, anorexia, ruffled feathers, weight loss, and lethargy and died finally. Gross necropsy revealed small areas of erosions and hemorrhages on the gizzard wall. The intestine was oedematous. The spleen appeared pale and small. The testes were asymmetric.Histologicall...

Besides their classical haemostatic task, platelets are now recognized as novel cells deeply involved in inflammation. Compelling evidence support their role as active player in mucosal tissue injury that occurs in Crohn's disease and ulcerative colitis. In both forms of inflammatory bowel disease platelets contribute to microvascular endothelial activation and recruitment of inflammatory cells...