The Australian Mycobacterium Reference Laboratory Network collects and analyses laboratory data on new cases of disease caused by the Mycobacterium tuberculosis complex. In 2011, a total of 1,057 cases were identified bacteriologically; an annual reporting rate of 4.6 cases per 100,000 population. Eighteen children aged less than 15 years plus an additional 11 children from the Torres Strait Pr...

23 15. Jahrgang | Heft 2/2006 | Chemotherapie Journal In the early 90’s a long neglected disease, tuberculosis, made it into the head lines of such prestigious journals like Science, Nature and New England Journal of Medicine. The reason for this was a frank disaster − the development of multi-drug resistance in Mycobacterium tuberculosis, the agent responsible for the disease. Multi-drug resis...

BACKGROUNDS Staphylococcus aureus has emerged as a major public health concern because of the occurrence of multi-drug resistant strains. This study aimed at investigating the multi-drug and vancomycin resistance profile of S. aureus from different infection sites in some teaching hospitals in Nigeria. METHODS Swabs were collected from different infection sites from out-patients in three teac...

The Australian Mycobacterium Reference Laboratory Network collects and analyses laboratory data on new cases of disease caused by the Mycobacterium tuberculosis complex. In 2010, a total of 1,051 cases were identified by bacteriology; an annual reporting rate of 4.7 cases per 100,000 population. Twelve children aged less than 10 years had bacteriologically-confirmed tuberculosis. Results of in ...

BACKGROUND & OBJECTIVES Information on drug resistance tuberculosis is sparse from North-East (N-E) States of India. We undertook this study to detect multi-drug resistant tuberculosis (MDR-TB) among MDR-TB suspects, and common mutations among MDR-TB cases using GenoType MTBDRplus. METHODS All MDR suspect patients deposited sputum samples to peripheral designated microscopy centres (DMC) in N...

Drug-resistant tuberculosis is a major public health problem. The aim of this study was to assess the local susceptibility patterns of Mycobacterium tuberculosis and clinical outcomes of drug resistant tuberculosis (DR-TB) at Srinagarind Hospital, a tertiary care center in northeastern Thailand. Between January 2004 and December 2008, 1,052 patients had culture-proven M. tuberculosis infections...

SETTING Nationwide Canadian public health surveillance. OBJECTIVE Description of demographic features and disease characteristics of drug-resistant tuberculosis (TB) in Canada over a 12 year period. DESIGN Continuous surveillance of all cases of culture-confirmed TB in Canada. Demographic and microbiologic features were analyzed and comparisons between drug-susceptible, multidrug-resistant ...

BACKGROUND Multi-drug resistance of Gram-negative bacteria constitutes a major obstacle in the antibacterial fight worldwide. The discovery of new and effective antimicrobials and/or resistance modulators is necessary to combat the spread of resistance or to reverse the multi-drug resistance. In this study, we investigated the antibacterial and antibiotic-resistance modifying activities against...

background : multi drug-resistant mycobacterium tuberculosis (mdr-tb) is an infection with a causative bacillus which is resistant to at least two drugs, isoniazid and rifampin. the purpose of this study is to evaluate the prevalence of tb resistance to first-line drugs of newly diagnosed active pulmonary tuberculosis. methods : this cross-sectional study was performed on 77 patients with newly...

background and objectives: tuberculosis (tb) is the major public health problem in the world. each year there are 2-3 million deaths worldwide caused by tb. the increasing incidence of multi drug resistance tuberculosis (mdr-tb) worldwide highlights the urgent need to search for new anti-tuberculosis compounds. it has been reported that medicinal plant, dracocephalum kotschyi, possesses some an...