In the treatment of cancer using high energetic radiation the problem arises how to irradiate the tumor without damaging the healthy tissue in the immediate vicinity. In order to do this as efficiently as possible intensity modulated radiation therapy (IMRT) is used. A modern way to modulate the homogeneous radiation field delivered by an external accelerator is to use a multileaf collimator in...

Leaf sequencing is an important step in IMRT treatment planning. A given fluence matrix has to be decomposed into a sum of binary matrices corresponding to fields deliverable with a multileaf collimator. We consider the problem to find such a decomposition with minimal delivery time. It is shown how the network flow formulation from [4] can be modified to take tongue-and-groove underdosage effe...

We have successfully created a single arc volumetric modulated arc therapy (VMAT) plan for treating post-surgical left breast/chest wall and regional nodes using Elekta multileaf collimator (MLC). Dose volume histograms (DVHs) were compared between the VMAT plans and conventional tangential beam plans using a field-in-field technique, leading to significant DVH advantages in the VMAT plans. The...