The cartilage-pannus junction has been studied in multiple sections from 23 rheumatoid joints. Changes suggesting a metaplastic reaction of the articular cartilage, termed transitional fibroblastic zone, were commonly found in hips and knees, but were rarely present in metatarsophalangeal joints, in which an invasive pannus with cartilage degradation in close association with inflammatory cells...

This paper advances a proposition for the engineering of interactive computer-based environments capable of exhibiting alternative interactive embodiments to cope with diversity in users, interaction platforms and usage contexts. Such systems are referred to as Multiple Metaphor Environments (MME). The theoretical underpinnings of an MME rely on a conception of HCI design as mapping functions i...

In this paper, a dynamic humanoid with a stair case model is designed to achieve a dynamically stable stair climbing gait pattern, and sequences of stair climbing locomotion analysis (weight acceptance, pull up, forward continuance, foot clearance and foot placement) are presented. A suitable trajectory control strategy is developed for the lower limb’s joints (hips, knees, ankles) during stair...

There are a huge number of bolted joints used in engineering applications. However, unreasonable design and use may lead to degradation failure the connected structure. Herein, finite element analysis method is investigate influence various factors on mechanical properties joints. To simulate actual assembly loading process, different steps were considered, given as: tightening step, initial lo...

Knuckle pads is a syndrome characterized by the presence of multiple nodules located on the extensor side of the interphalangeal or metacarpophalangeal joints. Several conditions can be confused with Knuckle pads. We describe a case of a 47-years-old man who developed multiple bilateral roundish nodules located in the skin over the dorsal and lateral interphalangeal joints in both hands.

Tunnel excavation is prone to segment cracks, which may lead serious safety accidents. This work aims investigate the type, location and occurrence time of cracks in a large-diameter underwater shield tunnel also ascertain causes cracks. The correlations between crack characteristics tunneling parameters were analyzed. effect jack deflection poor assembly on investigated using refined finite el...

the nasal cavity possesses many advantages as a site for drug delivery, such as, ease of administration, applicability for long term treatments and a large surface area for absorption. one important limiting factor for nasal drug delivery is the limited time available for absorption within the nasal cavity due to mucociliary clearance. several drug delivery systems including different kinds of ...