نتایج جستجو برای: multipotent

تعداد نتایج: 4785  

Journal: :Neuron 2000
Xueming Qian Qin Shen Susan K. Goderie Wenlei He Alexandra Capela Andrew A. Davis Sally Temple

Multipotent stem cells that generate both neurons and glia are widespread components of the early neuroepithelium. During CNS development, neurogenesis largely precedes gliogenesis: how is this timing achieved? Using clonal cell culture combined with long-term time-lapse video microscopy, we show that isolated stem cells from the embryonic mouse cerebral cortex exhibit a distinct order of cell-...

2013
Atsushi Shimomura Eri Hashino

During development, ESCs in the inner cell mass of the blastocyst undergo progressive fate restriction and sequentially give rise to tissue-specific multipotent progenitor cells [1-3]. In the nervous system, neural progenitor cells (NPCs) are defined as multipotent cells capable of differentiating into neurons and glia, the latter of which include astrocytes and oligoden‐ drocytes. NPCs undergo...

2013
Shengjuan Wei Linsen Zan Gary J Hausman Theodore P Rasmussen Werner G Bergen Michael V Dodson

Analyses of mature adipocytes have shown that they possess a reprogramming ability in vitro, which is associated with dedifferentiation. The subsequent dedifferentiated fat cells (DFAT cells) are multipotent and can differentiate into adipocytes and other cell types as well. Mature adipocytes can be easily obtained by biopsy, and the cloned progeny cells are homogeneous in vitro. Therefore, DFA...

Journal: :Proceedings of the National Academy of Sciences 2003

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