نتایج جستجو برای: mutant strains

تعداد نتایج: 270616  

Journal: :Infection and immunity 1989
R G Barletta R Curtiss

The Streptococcus mutans serotype c gtfA gene encodes a 55-kilodalton sucrose-hydrolyzing enzyme. Analysis of S. mutans gtfA mutants revealed that the mutant strains were specifically impaired in the ability to use melibiose as a sole carbon source. S. mutans gtfA mutant strains synthesized less alpha-galactosidase activity inducible by raffinose than wild-type strains. Melibiose (an inducer in...

Journal: :iranian journal of public health 0
s.mehrabian z. molabashi

five strains of mouth normal microflora containing staphylococcus epidermidis, streptococcus mutant, lactobacillus acidophilus, actinomyces viscosos and candida albicans, were isolated and identified then cultured and purified on different media by using routine methods in microbiology. extract of 3 garlic samples south (khuzestan), north (mazanderan) and hamedan garlics, were affected on these...

Journal: :jundishapur journal of microbiology 0
samia siddique department of chemistry, government college university lahore, lahore, pakistan quratulain syed food and biotechnology research center, pcsir laboratories complex, ferozpur lahore, lahore, pakistan ahmad adnan department of chemistry, government college university lahore, lahore, pakistan fahim ashraf qureshi office of research, innovation and commercialization, comsats institute of information and technology, islamabad, pakistan; office of research, innovation and commercialization, comsats institute of information and technology, islamabad, pakistan. tel: +92-3334101261, fax: +92-519247008

conclusions: the hereditary stability analysis of the uv mentioning 45 minutes revealed the uv exposure time for mutants and 3 represented the colony taken from the plate irradiated for 45 minutes mutant showed that the production of avermectin b1b remained constant and no reverse mutation occurred after 15 generations. results: avermectin b1b-hyper-producing mutant, produced using these three ...

2017
Alex Mas Monteys Shauna A. Ebanks Megan S. Keiser Beverly L. Davidson

Huntington disease (HD) is a fatal dominantly inherited neurodegenerative disorder caused by CAG repeat expansion (>36 repeats) within the first exon of the huntingtin gene. Although mutant huntingtin (mHTT) is ubiquitously expressed, the brain shows robust and early degeneration. Current RNA interference-based approaches for lowering mHTT expression have been efficacious in mouse models, but b...

2017
Hélène Le Guillou-Guillemette Adeline Pivert Elise Bouthry Cécile Henquell Odile Petsaris Alexandra Ducancelle Pascal Veillon Sophie Vallet Sophie Alain Vincent Thibault Florence Abravanel Arielle A Rosenberg Elisabeth André-Garnier Jean-Baptiste Bour Yazid Baazia Pascale Trimoulet Patrice André Catherine Gaudy-Graffin Dominique Bettinger Sylvie Larrat Anne Signori-Schmuck Hénia Saoudin Bruno Pozzetto Gisèle Lagathu Sophie Minjolle-Cha Françoise Stoll-Keller Jean-Michel Pawlotsky Jacques Izopet Christopher Payan Françoise Lunel-Fabiani Christophe Lemaire

BACKGROUND The emergence of new strains in RNA viruses is mainly due to mutations or intra and inter-genotype homologous recombination. Non-homologous recombinations may be deleterious and are rarely detected. In previous studies, we identified HCV-1b strains bearing two tandemly repeated V3 regions in the NS5A gene without ORF disruption. This polymorphism may be associated with an unfavorable...

2013
Seung-Rak Kim Hyeon-Woo Kang Hyeon-Su Ro

A chemical mutagenesis technique was employed for development of mutant strains of Sparassis crispa targeting the shortened cultivation time and the high β-glucan content. The homogenized mycelial fragments of S. crispa IUM4010 strain were treated with 0.2 vol% methyl methanesulfonate, an alkylating agent, yielding 199 mutant strains. Subsequent screening in terms of growth and β-glucan content...

Journal: :Journal of bacteriology 2000
P J McNamara K C Milligan-Monroe S Khalili R A Proctor

A chromosomal insertion of transposon Tn917 partially restores the expression of protease and alpha-toxin activities to PM466, a genetically defined agr-null derivative of the wild-type Staphylococcus aureus strain RN6390. In co-transduction experiments, transposon-encoded erythromycin resistance and a protease- and alpha-toxin-positive phenotype are transferred at high frequency from mutant st...

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