نتایج جستجو برای: myelin basic protein
تعداد نتایج: 1490887 فیلتر نتایج به سال:
BACKGROUND AND OBJECTIVE Acute disseminated encephalomyelitis (ADEM) and relapsing-remitting multiple sclerosis (RRMS) share overlapping clinical, radiologic and laboratory features at onset. Because autoantibodies may contribute to the pathogenesis of both diseases, we sought to identify autoantibody biomarkers that are capable of distinguishing them. METHODS We used custom antigen arrays to...
Clinical exacerbations of multiple sclerosis (MS) are characterized by elevated levels of cerebrospinal fluid (CSF) myelin basic protein (MBP). The purposes of this study were to determine whether anti-MBP antibodies are present in increased titer in CSF of MS patients with exacerbations, and whether they can be suppressed by the administration of immunosuppressive dosages of methylprednisolone...
Encephalitogenic basic protein and the enzyme nucleoside 2' :3'-cyclic monophosphate 3'-phosphodiesterase (EC 3.1.4.16) are recognized markers for myelin. Phosphodiesterase activity can be detected in the brains of newborn rats even though myelin cannot be seen by light or electron microscope. The determination of phosphodiesterase activity and the detection of basic protein by Coomassie-Blue s...
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