نتایج جستجو برای: myelodysplastic syndromes

تعداد نتایج: 86513  

Journal: :Clinical and laboratory haematology 1984
D A Galton

The concept of preleukaemia originated early in this century with the recognition of prodromal haematological abnormalities in acute myeloid leukaemia.' Since then similar preleukaemic disorders have 'been described, including primary acquired sideroblastic anaemia and smouldering or oligoblastic leukaemia. Confusion created by differing connotations placed on the term preleukaemia was resolved...

Journal: :Journal of the National Comprehensive Cancer Network : JNCCN 2015
Peter L Greenberg Richard M Stone Rafael Bejar John M Bennett Clara D Bloomfield Uma Borate Carlos M De Castro H Joachim Deeg Amy E DeZern Amir T Fathi Olga Frankfurt Karin Gaensler Guillermo Garcia-Manero Elizabeth A Griffiths David Head Virginia Klimek Rami Komrokji Lisa A Kujawski Lori J Maness Margaret R O'Donnell Daniel A Pollyea Bart Scott Paul J Shami Brady L Stein Peter Westervelt Benton Wheeler Dorothy A Shead Courtney Smith

The NCCN Guidelines for Myelodysplastic Syndromes (MDS) comprise a heterogeneous group of myeloid disorders with a highly variable disease course that depends largely on risk factors. Risk evaluation is therefore a critical component of decision-making in the treatment of MDS. The development of newer treatments and the refinement of current treatment modalities are designed to improve patient ...

2016
Elias Jabbour Hagop M Kantarjian Guillermo Garcia-Manero Jean-Pierre J Issa

2011
Elena Liew Carolyn Owen

Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematopoietic stem cell disorders characterized by dysplastic changes in the bone marrow, ineffective hematopoiesis resulting in cytopenias, and an increased risk of developing acute myeloid leukemia (AML). MDS is predominantly a sporadic disease that affects the elderly, with a median age of diagnosis of over 70 years, and gen...

Journal: :Annual Review of Pathology: Mechanisms of Disease 2013

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