Thyroid emergencies are major life-threatening endocrine conditions associated with life-threatening disorders resulting from either severe deficiency or excess of thyroid hormones. Deficiency of thyroid hormones may present as myxedema coma whereas excessive hormone production can present as life threatening thyrotoxic storm. The diagnosis of both requires a high index of clinical suspicion. T...

Nineteen dogs were given 13'I and later administered appropriate amounts of methimazole or propylthiouracil daily. Over a period of 4-7 years several developed severe clinical features of myxedema. The myocardium and skeletal muscle of these severely myxedematous dogs displayed an array of morphologic changes on an ultrastructural level. Particularly interesting was the twoto threefold increase...

An analysis of the blond and CSF protein concentration and lipid profiles in 14 patients with clinical myxedema has been presented. In addition, the serum and CSF bromide concentrations were measured following the oral administration of sodium bromide during the preand post-treatment period. While the serum lipids and protein concentrations were noted to be elevated prior to treatment, the CSF ...

To the Editor: " Myxedema madness " is a severe, complicated form of psychosis due to significant hypothyroidism. Although literature exists illustrating psychiatric symptoms (eg, depression , lethargy) as a result of hypothyroidism, psychosis associated with hypothyroidism is often overlooked. Additionally, published literature varies on the nature of psychotic symptoms present (eg, Capgras sy...

Myxedema crisis is an extreme complication of uncontrolled hypothyroidism. It is usually seen in elderly women with undiagnosed hypothyroidism and is rare among young. There have been very few reports of myxedema coma in labor. This report pertains to a case of undiagnosed hypothyroidism in a 30 year old lady with twin pregnancy which led to hypothyroidism crisis during labor. Levothyroxine 100...

The endocrinological emergency of a fully blown myxedema crisis can present as a multicolored clinical picture. This can obscure the underlying pathology and easily lead to mistakes in clinical diagnosis, work-up, and treatment. We present a case of an unconscious 39-year-old patient with a medical history of weakness, lethargy, and findings of hyponatremia, intracerebral bleeding, and massive ...

Pericardial effusion is frequently found in patients diagnosed with hypothyroidism, yet it is rarely associated with cardiac tamponade. This report presents an atypical case concerning a 60-year-old Taiwanese female, with a history of thyroidectomy surgery due to thyroid cancer, who was later diagnosed with myxedema and cardiac tamponade. Treatment included an immediate pericardiocentesis follo...