Interleukin (IL)-27 is a cytokine of the IL-12 family that displays either immunostimulatory or immunosuppressive functions depending on the context. In various murine tumor models including melanoma models, ectopic expression of IL-27 has been shown to play an anti-tumoral role and to favor tumor regression. In this study, we investigated whether IL-27 might play a role in the development of m...

We enumerate rooted 3-connected (2-connected) planar triangulations with respect to the vertices and 3-cuts (2-cuts). Consequently, we show that the distribution of the number of 3-cuts in a random rooted 3-connected planar triangulation with n+3 vertices is asymptotically normal with mean (10/27)n and variance (320/729)n, and the distribution of the number of 2-cuts in a random 2-connected pla...

CNRS UMR 8557. Paris 27.

E-government refers to the use of information and communication technologies for improving government services and interactions with citizens. In today’s digital information era the successful delivery of public policy is of paramount importance and significantly dependent upon the effective technology deployment. In this respect, many researches and business organizations have studied the mean...

Acute pharyngitis is one of the most common illnesses for which children in the United States visit primary care providers; pediatricians make the diagnosis of acute pharyngitis, acute tonsillitis, or “strep throat” more than 7 million times annually. A partial list of the more common microorganisms that can cause acute pharyngitis is presented in Table 27-1. Most cases in children and adolesce...

Thin-shell instability is one process which can generate entangled structures in astrophysical plasma on collisional (fluid) scales. It is driven by a spatially varying imbalance between the ram pressure of the inflowing upstream plasma and the downstream's thermal pressure at a nonplanar shock. Here we show by means of a particle-in-cell simulation that an analog process can destabilize a thin...

The topic of Hamiltonian chaos is a whole course in itself, and we will only touch on a few highlights. For further information see Ott chapter 7, and review papers by Berry [1] and Helleman [2]. The ideal pendulum discussed in chapter 2 is an example of a Hamiltonian system. In many ways this system is typical of the ones taught in elementary courses on mechanics: the orbits are periodic and c...

Background. The contributions of patients’ opinions to the evaluation of health care is widely acknowledged. This study investigates whether the patients of a fundholding practice perceived any changes in the services offered. Aim. To examine the effect of general practice fundholding on patient satisfaction with both primary and secondary care services. Method. In April 1992, questionnaires we...

27.1 Features . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 311 27.2 Success Stories . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 313 27.3 Conclusion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 315 Bibl...