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objective: surgery is considered the primary treatment for male infertility from clinical varicocele. one of the main events associated with varicocele is excessive production of reactive oxygen species (ros). n-acetyl-l-cysteine (nac), an antioxidant that scavenges free radicals, is considered a supplement to alleviate glutathione (gsh) depletion during oxidative stress. despite beneficial eff...

Abstract: Seeds of the genus Eugenia L. (Myrtaceae) have interesting propagation strategies, and reactive oxygen species (ROS) seem to be related their germination seedling production. In this study, effects ROS on E. involucrata seeds were analyzed indirectly, with application N-acetyl-L-cysteine (NAC), an antioxidant. The results demonstrated that incubation in NAC suppressed and/or delayed s...

Swertia mileensis, known as Qing-Ye-Dan (QYD), has been documented in Chinese Pharmacopoeia to cure hepatitis. Interestingly, its announced main active component, swertiamarin, could not be detected the decoction, which indicated that efficacy of QYD might attributed heat-transformed products swertiamarin (HTPS). Further investigation on HTPS led isolation sweritranslactone D (1), a novel secoi...