background: the poor permeability of the plasma and nuclear membranes to dna plasmids are two major barriers for the development of these therapeutic molecules. therefore, success in gene therapy approaches depends on the development of efficient and safe non-viral delivery systems. objectives: the aim of this study was to investigate the in vitro delivery of plasmid dna encoding hpv16 e7 gene ...

in this paper, plate-like nio nanoparticles were prepared by one-pot solid-state thermal decomposition of nickel (ii) schiff base complex as new precursor. first, the nickel (ii) schiff base precursor was prepared by solid-state grinding using nickel (ii) nitrate hexahydrate, ni(no3)2∙6h2o, and the schiff base ligand n,n′-bis-(salicylidene) benzene-1,4-diamine) for 30 min without using any solv...

The reduction of [Pt(COD)(CH3)2] with CO in the presence of hexadecylamine (HDA) and oleic acid (OlAc) leads to amine carbonylation and formation of an air-stable colloidal solution of N,N'-bis(hexadecyl)urea-stabilized Pt(0) nanoparticles. These air-stable colloidal solutions can be used to form thin films of Pt nanoparticles on a silicon substrate.

A general approach for producing biodegradable nanoparticles for sustained nucleic acid release is presented. The nanoparticles are produced by precipitating a water-in-oil microemulsion in supercritical CO(2). The microemulsion consists of a transfer RNA aqueous solution (water phase), dichloromethane containing poly(l-lactic acid)-poly(ethylene glycol) (oil phase), the surfactant n-octyl β-D-...

biomolecules, they can be used to locate cancerous areas and for drug delivery. 10 15 20 25 30 35 40 45 50 1 Multifunctional nanoparticles as biocompatible targeted Ken-Tye Yong, Indrajit Roy, Mark T. Swihart and Paras N. Prasad The use of nanoparticles in biological applications has been advancing toward applications in human cancer diagnosis and therapy. Upon functionalizing the nanoparticles...

The oxidative doping of single poly(N-vinylcarbazole) (PVK) nanoparticles is reported in aqueous sodium perchlorate using the nanoimpact method. Complete oxidative doping of single PVK nanoparticles with a size of approximately 120 nm is demonstrated, showing for the first time a simple strategy to synthesize and characterize doped polymeric nanoparticles at the single nanoparticle level.

Alkanethiol-capped gold nanoparticles dispersed in n-dodecane were studied by spectroscopic ellipsometry and were modeled using Mie scattering theory. The refractive index in the visible and near-infrared depended on the volume fraction of gold nanoparticles, in good agreement with the theoretical expectation that such dispersed plasmonic nanoparticles can act as low or tunable refractive index...

Title of Dissertation: DEVELOPMENT OF SELF-ASSEMBLED ZnO NANOSTRUCTURES IN DIBLOCK COPOLYMERS ON LARGE AREA Si WAFERS AND GAS SENSOR APPLICATIONS Hasina Afroz Ali, Doctor of Philosophy, 2008 Dissertation Directed By: Agis A. Iliadis Department of Electrical and Computer Engineering ZnO nanoparticles with improved optical properties and increased surface areas have the potential for advanced opt...

Spin-crossover compounds are a class of materials that can change their spin state from high spin (HS) to low spin (LS) by external stimuli such as light, pressure or temperature. Applications demand compounds with defined properties concerning the size and switchability that are maintained when the compound is integrated into composite materials. Here, we report the synthesis of [Fe(Leq)(Lax)]...

Investigating active, stable, and low-cost materials for the oxygen reduction reaction is one of the key challenges in fuel-cell research. In this work, we describe the formation of N-doped carbon shell coated Co@CoO nanoparticles supported on Vulcan XC-72 carbon materials (Co@CoO@N-C/C) based on a simple supramolecular gel-assisted method. The double-shelled Co@CoO@N-C/C core-shell nanoparticl...