Crotoxin, the first crystalline protein from snake venom isolated by Slotta and Fraenkel-Conrat (1) in 1938 from the venom of Crotalus terr$cus terr$icus, carried both neurotoxic and hemolytic activities. However, it was found later that there were at least two markedly different proteins in this crystalline preparation (2). In 1944, De (3) isolated crystalline hemolysin from the venom of Naja ...

Previous studies reported that Naja naja atra venom (NNAV) inhibited inflammation and adjuvant arthritis. Here we investigated the role of NNAV in regulation of immune responses in mice. Oral administration of NNAV to normal mice showed significant increase in natural killer cell activity, B lymphocyte proliferation stimulated by lipopolysaccharides, and antibody production in response to sheep...

Indian cobra (Naja naja) venom from different geographical locations varied in its composition and biochemical, pharmacological and immunological properties. Recently it has been shown that the variation in composition of venom from different geographical origin of Indian peninsula is due to the quantitative difference in the same components and also the presence of different biochemical entiti...