Abstract Objectives The current study was focused on preparing curcumin (CUR) supersaturated self-nano-emulsion (PI-CUR-SNEDDS) using hydrophilic polymer and to the influence of precipitation inhibitor physicochemical biopharmaceutical properties PI-CUR-SNEDDS. Methods PI-CUR-SNEDDS were prepared in order maintain supersaturation CUR nano-emulsion solution, artificial gastrointestinal fluid (AG...

In line with the application of green techniques in recovery bioactive compounds, this research study aimed to evaluate efficiency supercritical Co2 and water distillation extraction sweet basil essential oil. addition, effect wall material made native gums as well Lepidium sativum (LS), perfoliatum (LP), a combination both (LP/LS), following freeze-drying method, on Nano-emulsion properties en...

To compare the efficacy of L-DOPA administered intranasally in the form of nanoparticles (nano-DOPA) and in standard drug forms using a rat Parkinson's Disease (PD) model. L-DOPA-containing nanoparticles (250±50 nm) were synthesized using the double emulsion method. The efficacy of nano-DOPA therapy was studied in Wistar rats with 6-OHDA-induced PD. Drugs were administered daily, 0.35 mg/kg (by...

COVID-19 is a highly infectious respiratory disease that resulted in global pandemic has affected every stage and sector of life. Although it mainly seen as health issue, its impacts ripple effects also resonated the education, technology, agriculture, research fields, creating socio-economic disruptions across globe. In bid to curb wide spread disease, diverse sudden restriction measures were ...