نتایج جستجو برای: nanoliposome
تعداد نتایج: 140 فیلتر نتایج به سال:
Cancer is a fatal disease and relatively widespread in the world; Breast cancer is the most prevalent cancer among women. Hydroxyurea (HU) is a chemotherapy drug for the cure of cancer different types in patients, for example breast cancer, but has several defects, for to remove these problems in this study a nanoliposome (NL) suspension for Hydroxyurea (HU) delivery in breast cancer cell thera...
Increasing consumption of tobacco and alcohol has led to a steady increase in the incidence of head and neck cancers in Asia. The drawbacks associated with the existing chemotherapeutic and surgical interventions have necessitated the development of a safer alternative for therapy of head and neck cancers. In this study we have explored the synergistic therapeutic potential of a phytochemical a...
Nanoliposomal formulation of C6-ceramide, a proapoptotic sphingolipid metabolite, presents an effective way to treat malignant tumor. Here, we provide evidence that acute treatment (30 min) of melanoma and breast cancer cells with nanoliposomal C6-ceramide (NaL-C6) may suppress cell migration without inducing cell death. By employing a novel flow migration assay, we demonstrated that NaL-C6 dec...
Lysosomal storage disorders (LSD) are caused by lysosomal dysfunction usually as a consequence of deficiency of a single enzyme required for the metabolism of macromolecules, such as lipids, glycoproteins, and mucopolysaccharides. For instance, the lack of α-galactosidase A (GLA) activity in Fabry disease patients causes the accumulation of glycosphingolipids in the vasculature leading to multi...
While artemisinin is known as anticancer medication with favorable remedial effects, its side effects must not be neglected. In order to reduce such side effects and increase artemisinin therapeutic index, nano technology has been considered as a new approach. Liposome preparation is supposed to be one of the new methods of drug delivery. To prepare the desired nanoliposome, certain proportions...
OBJECTIVE The goal of the present study was to formulate topical nanocarriers of the low-cost vasodilator, papaverine hydrochloride (PH), as an alternative to the painful penile injections. The injections are used for both diagnosis and treatment of erectile dysfunction. Transdermal nano-transferosome (T), the ultraflexible nanoliposome, was used as a nanocarrier to enhance the penetration of t...
Abstract Cellular senescence and the senescence-associated secretory phenotype (SASP) have been implicated in osteoarthritis (OA). This study aims to determine whether multi-kinase inhibitor YKL-05-099 (Y099) has potential elimination OA therapy delivering Y099 by nanoliposmal hydrogel improves performance of kinase inhibitor. inhibited IL-1β-induced inflammation catabolism promoted anabolism c...
In this study, the effects of chitosan film (1 and 2%) containing rosemary essential oil (1%) in free nanoliposome forms were investigated on physicochemical, microbial, organoleptic, oxidation characteristics chicken burgers during storage (day 1, day 10, 20) at 4°C. The results showed that decreased pH, total volatile basic nitrogen compounds (TVB-N), parameters (peroxide value thiobarbituric...
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