Submit Manuscript | http://medcraveonline.com of nanostructures with the biological system of human being. Nanotoxicity occurs when biological system induces toxic biological responses due to the interaction with the properties of nanostructures either physical properties, chemical properties or both. Nanostructures include Nanoparticles, Nanotubes, Nanometals, Nanowire, Nanoballs and Nanocapsu...

Until now, the results of nanotoxicology research have shown that the interactions between nanoparticles (NPs) and cells are remarkably complex. In order to get a deep understanding of the NP-cell interactions, scientists have focused on the physicochemical effects. However, there are still considerable debates about the regulation of nanomaterials and the reported results are usually in contra...

Gangwal et al. (2011) addressed an important topic for nanotoxicology about assessing the toxicity of inhaled nano materials by recom mending relevant concentrations for in vitro toxicity testing. Their efforts to select in vitro concentrations based on reported occupational exposure levels of inhaled nano materials are, indeed, laudable. Their under lying conceptual approach is logical, involv...

Analysis of trends in nanotoxicology data and the development of data driven models for nanotoxicity is facilitated by the reporting of data using a standardised electronic format. ISA-TAB-Nano has been proposed as such a format. However, in order to build useful datasets according to this format, a variety of issues has to be addressed. These issues include questions regarding exactly which (m...