What is the higher-dimensional analog of a permutation? If we think of a permutation as given by a permutation matrix, then the following definition suggests itself: A d-dimensional permutation of order n is an n × n × . . . n = [n]d+1 array of zeros and ones in which every line contains a unique 1 entry. A line here is a set of entries of the form {(x1, . . . , xi−1, y, xi+1, . . . , xd+1)|n ≥...

A slight reduction of the ozone level over the northern hemisphere in the period 1969-1986 has been reported (D. Lindley, Nature (Lond.), 323: 293, 1988). Ozone measurements performed in Oslo are in agree ment with this. However, the ozone level for 1987 and 1988 was above normal, and no negative or positive trend is apparent for the last 10 years. The consequences of an ozone reduction for the...

The DMA content of murine fibrosarcoma cell lines of various metastatic potential was the subject of the current investigation. The cell lines were derived from methylcholanthrene-induced tumors as described previously (J. Varani ef al., J. Nati. Cancer Inst., 71: 1281-1287,1983). Cells were maintained in vitro and used for DNA studies no more than 48 h after passage. DNA staining was accomplis...

Murer, Heini, Ian Forster, Nati Hernando, Georg Lambert, Martin Traebert, and Jürg Biber. Posttranscriptional regulation of the proximal tubule NaPi-II transporter in response to PTH and dietary Pi. Am. J. Physiol. 277 (Renal Physiol. 46): F676–F684, 1999.—The rate of proximal tubular reabsorption of phosphate (Pi) is a major determinant of Pi homeostasis. Deviations of the extracellular concen...

The synthesis of a unique protein with a molecular weight of 32,000 (p32) in BALB/c 3T3 cells has been shown previously to increase after treatment with potent tumor-promoting phorbol esters (Hiwasa ef al., Proc. Nati. Acad. Sei. U. S. A., 79: 1800, 1982). In the present study, two new classes of tumor promoters which are structurally different from phorbol esters were inves tigated for their p...

New sublines of Chinese hamster CHL cells stably expressing human NATI or NAT2 A'-acetyltransferases or 0-acetyltransferase of Salmonella typhimurium were established, and their sensitivities to carcinogenic nitroarenes and aromatic amines were compared using the in vitro micronucleus test. The subline expressing human NAT2 A'-acetyltransferase exhibited the highest sensitivity to the ciastogen...

1. Kahn A, Cottreau D, Boyer C, Marie J, Galand C, Boivin P: Causal mechanisms of multiple acquired red cell enzyme defects in a patient with acquired dyserythropoiesis. Blood 48:653-662, 1976 2. Rochant H, Dreyfus B, Bouguerra M, Tont-Hat H: Hypothesis: Refractory anemias, preleukemic conditions, and fetal erythropoiesis. Blood 39:72l -726, 1972 3. Kahn A, Boivin P. Rubinson H, Cottreau D, Mar...

Previous experiments have demonstrated specific inhibition of tumor formation after neuroblastoma cells were injected into fragments of 8.5to 9.5-day embryonic tissue (A. H. Podestà et ai. Proc. Nati. Acati. Sci. USA, 81: 7608-7611, 1984). The effect was localized to the somite and appeared specific for neuroblastoma as opposed to a variety of other tumor types. This regulation of neuroblastoma...

This study examined the relationships among objective and subjective risk for breast cancer and mammography stages of change as defined by the Transtheoretical Model. Women who had higher objective risk of breast cancer, as defined by the Gail et al. algorithm (M. H. Gail et aL, J. Nati. Cancer Inst., 81: 1879-1886, 1989), were more likely to perceive themselves at greater subjective risk for b...

The glutathione transferase P (GST-P) gene is known for its specific expression during chemical hepatocarcinogenesis of the rat and is used as a tumor marker for hepatocellular carcinoma. We have shown recently that the upstream 2.9-kb region of the GST-P gene is sufficient for conferring tumor-specific expression of the gene in vivo (S. Morimura et al., Proc. Nati. Acad. Sci. USA, 90: 2065-206...