In silico investigations of the natural bioactive compounds in microalgae from mangrove tropical estuaries showed an influence on heat shock protein -70 production. Incorporation algae with such diet copepod high density culture might lead to enhanced egg For this study, structure ligands (bioactive region estuary) and X-ray crystal hsp-70 complex was taken PDB (3P9Y) a resolution 2.10 Å. The m...

An endophytic fungus isolated from the plant Cinnamomum mollissimum was investigated for the bioactivity of its metabolites. The fungus, similar to a Phoma sp., was cultured in potato dextrose broth for two weeks, followed by extraction with ethyl acetate. The crude extract obtained was fractionated by high-performance liquid chromatography. Both crude extract and fractions were assayed for cyt...

Marine algae are known to contain a wide variety of bioactive compounds, many of which have commercial applications in pharmaceutical, medical, cosmetic, nutraceutical, food and agricultural industries. Natural antioxidants, found in many algae, are important bioactive compounds that play an important role against various diseases and ageing processes through protection of cells from oxidative ...

In the present study, possible cytochrome enzyme inhibition potential of Aegle marmelos (L.) Corrêa fruit and its bioactive compound was evaluated. Interaction potential of Aegle marmelos extract was evaluated through CYP450carbonmonoxide complex (CYP450-CO) assay. Additionally, influence on individual major human cytochrome P450 drug metabolizing enzymes such as CYP3A4, CYP2D6, CYP2C9 and CYP1...

Implication for health policy/practice/research/medical education: It provides recent information regarding active marine natural products which can be utilized in pharmacy and medicine. Copyright © 2014, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences; Published by DOCS. This is an open-access article distributed under the terms of the Creative Commons Attribution License,...

Cyanobacteria are widely recognized as a valuable source of bioactive metabolites. The majority of such compounds have been isolated from so-called complex cyanobacteria, such as filamentous or colonial forms, which usually display a larger number of biosynthetic gene clusters in their genomes, when compared to free-living unicellular forms. Nevertheless, picocyanobacteria are also known to hav...

The demand for healthy ingredients and a natural way of preventing diseases is contributing to the increased use of natural matrices. There has been a lot of research indicating that general antioxidant properties are not the contributing factors to improving human health but rather the antioxidant properties of specific compounds involved in specific cell signaling mechanisms that need to be e...

Natural products (NPs) have been optimized in a very long natural selection process for optimal interactions with biological macromolecules. NPs are therefore an excellent source of validated substructures for the design of novel bioactive molecules. Various cheminformatics techniques can provide useful help in analyzing NPs, and the results of such studies may be used with advantage in the dru...