The overall objective of the present work was to develop an oral sustained-release (SR) Metformin tablet that is prepared by direct compression method using hydrophilic hydroxyl propyl methyl cellulose (HPMC) and Guar gum polymer alone as well in combination at different concentrations. a biguanide has relatively short plasma half-life. It low absolute bioavailability. All properties were evalu...

The synthesis of an oriented liquid-crystalline photoresponsive polymer, prepared by polymerization of mono- and di-acrylates, both of which contain azobenzene chromophores, is reported. The prepared free-standing polymer film shows strong reversible photoinduced deformation upon exposure to unpolarized UV light at 366 nm, as a result of an optically induced isomeric change of the azobenzene mo...

This research study compares the effect of polypropylene and wool fibers on the mechanical properties of natural polymer based stabilized soils. Biocomposites are becoming increasingly prevalent and this growth is expected to continue within a number of sectors including building materials. The aim of this study was to investigate the influence of different fiber reinforced natural polymer stab...

In recent years, researchers have focused on targeted gene therapy for lung cancer, using nanoparticle carriers to overcome the limitations of conventional treatment methods. The main goal of targeted gene therapy is to develop more efficient therapeutic strategies by improving the bioavailability, stability, and target specificity of gene therapeutics and to reduce off-target effects. Polymer-...

Object: The objective of the present study was to investigate the effect of various concentrations of natural and synthetic polymers on in vitro drug release from sustained release matrix tablets. Materials and method: HPMC K4M and acacia gum were used as synthetic (hydrophilic) and natural (hydrophobic) polymers respectively. Diclofenac sodium was used as a model drug to study the in vitro rel...

Inertness and the indiscriminate use of synthetic polymers leading to increased land and water pollution are of great concern. Plastic is the most useful synthetic polymer, employed in wide range of applications viz. the packaging industries, agriculture, household practices, etc. Unpredicted use of synthetic polymers is leading towards the accumulation of increased solid waste in the natural e...