Use of natural noncaloric sweeteners in commercial foods and beverages has expanded recently to include compounds from the plant Stevia rebaudiana. Little is known about the responses of rodents, the animal models for many studies of taste systems and food intake, to stevia sweeteners. In the present experiments, preferences of female Sprague-Dawley rats and C57BL/6J mice for different stevia p...

Artificial sweeteners or intense sweeteners are sugar substitutes that are used as an alternative to table sugar. They are many times sweeter than natural sugar and as they contain no calories, they may be used to control weight and obesity. Extensive scientific research has demonstrated the safety of the six low-calorie sweeteners currently approved for use in foods in the U.S. and Europe (ste...

Running Title: Non-correlation of observables in calcium flux assay of sweet taste receptors ! #! !"#$%&'$! ! Validation of research methodology is critical in research design. Correlation between experimental observables must be established before undertaking extensive experiments or propose mechanisms. This article shows that, observables in the popular calcium flux strength assay used in the...

The prevalence of obesity and diabetes has increased exponentially in recent years around the globe, especially in India. Sweet proteins have the potential to substitute the sugars, by acting as natural, good and low calorie sweeteners. They also do not trigger a demand for insulin in diabetic patients unlike sucrose. In humans, the sweet taste perception is mainly due to taste-specific G prote...

Submit Manuscript | http://medcraveonline.com rat urine. Therefore, Saccharin induced may not be relevant to any risk to human health [1-3]. On the other hand, reports published by The European Food Safety Authority [4] indicate that low concentrations of low-calorie sweeteners are safe to be consumed by humans. Further research is needed to relate the results obtained from animal studies in or...

Xylitol (1) is a pentitol and is used not only as a sweetener but also as a platform chemical for the production of industrially important chemicals. As a sweetener, it has been shown to possess several favorable properties in comparison to other sugar substitutes, such as anticariogenicity, good gastrointestinal tolerance, low caloric content, and minimal insulin dependence for metabolism. As ...

One of the questions arising in studying taste transduction is whether natural sweets are distinguished from sweeteners as the former are the major source of metabolic energy. Blowflies are a convenient preparation to study chemoreception, given their relatively simplicity, availability and the vast body of related work published. The labellar chemosensory system of blowflies consists of sensil...