Epithelial-mesenchymal transition (EMT) is an essential morphogenetic process during embryonic development. It can be induced in vitro by hepatocyte growth factor/scatter factor (HGF/SF), or by FGF-1 in our NBT-II cell model for EMT. We tested for a central role in EMT of a zinc-finger protein called Slug. Slug mRNA and protein levels were increased transiently in FGF-1-treated NBT-II cells. Tr...

Abstract Background Different trials showed that patients treated with blood transfusion (BT) have unfavorable prognosis regarding outcomes and mortality. Nevertheless, in BT hospitalized a contemporary tertiary intensive cardiac care unit (ICCU) is limited. Objective To determine mortality rate ICCU. Methods A prospective single center study to evaluate short- long-term of between January 2020...

Cytochrome b558 of pig blood neutrophils was purified from the membranes of resting cells to examine its ability to reconstitute superoxide (O2-)-forming NADPH oxidase activity in a cell-free assay system containing cytosol and fatty acid. The membrane-associated cytochrome b558 was solubilized with a detergent, n-heptyl beta-thioglucoside, and purified by DEAE-Sepharose, heparin-Sepharose, and...

Thiopurine and its derivatives, including azathioprine (AZA), 6mercaptopurine (6-MP), and 6-thioguanine (6-TG) have been used as pro-drugs in cancer treatment and inflammatory bowel disease. However, unlike canonical DNA and RNA bases that mainly absorb UVC (100-280 nm) and UVB (280-320 nm) light, thiopurine bases are strong UVA (320-400 nm, covering 90% solar UV irradiation) chromophores and s...

OBJECTIVE To develop an application that is simple and reliable using the nitroblue tetrazolium (NBT) method that clearly differentiates chronic granulomatous disease (CGD) patients with heterozygous carriers in groups suspected with CGD. METHODS This study was carried out in Shiraz University of Medical Sciences from October 2002 and March 2004. The study included 260 samples consisting of 1...

Na1/2Bi1/2TiO3-based relaxor ferroelectrics are extensively investigated for use in transduction applications because of their relatively large electromechanical properties. Integration these materials into devices, however, requires better temperature stability addition to This work demonstrates a novel approach enhance the long-range ferroelectric order as well properties non-ergodic 0.93(Na1...

The local symmetry of (1-x)Na0.5Bi0.5TiO3-xKNbO3 (NBT-xKN, x = 0.01−0.07) ceramics was thoroughly examined using high-energy synchrotron x-ray scattering and analysed the pair distribution function (PDF) method. At room temperature, structure NBT-xKN (x best refined monoclinic C1c1 structures within local-range (r<22 Å) rhombohedral R3c medium-range (22 Å <r <52 Å). Furthermore, exists from tem...

PURPOSE To assess the safety and usefulness of neutron brachytherapy (NBT) as an adjuvant in the treatment of patients with gastroesophageal junction adenocarcinoma (GEJAC) with external beam radiation (EBRT), with or without chemotherapy. METHODS AND MATERIALS In total, 197 patients with localized, advanced GEJAC received EBRT and NBT with or without chemotherapy. Radiotherapy consisted of e...

A study of leucocyte response to infection, polymorphonuclear leucocyte chemotaxis and bactericidal activity, and nitroblue tetrazolium (NBT) reduction in children with kwashiorkor was undertaken and compared with a control group. The results show that total leucocyte counts were depressed in children with kwashiorkor, and lymphopenia was not infrequent. NBT reduction was normal. Abnormal polym...