The growth of mammary carcinoma induced by oral 3-methylcholanthrene in female Wistar rats is retarded by ovariectomy and by food restriction sufficient to produce 12-14% body weight loss. Estradici benzoate (NSC 9566), 5-fluorouracil (NSC 19893), miracil D (NSC 14574), mitomycin C (NSC 26980), and AB-100 (NSC 37095) showed inhibitory activity. The best tumor inhibition without mortality was el...

We model the effects of collisions and close encounters on stellar populations observed in Milky Way nuclear cluster (NSC). Our analysis is based $N$-body simulations which NSC forms by accretion massive clusters around a supermassive black hole. attach to our particles follow evolution their stars, rate encounters. The most common are between pairs main-sequence lead mergers: destructive stars...

Proinflammatory factors from activated T cells inhibit neurogenesis in adult animal brain and cultured human fetal neural stem cells (NSC). However, the role of inhibition of neurogenesis in human neuroinflammatory diseases is still uncertain because of the difficulty in obtaining adult NSC from patients. Recent developments in cell reprogramming suggest that NSC may be derived directly from ad...

Transport of 5-(dimethyltriazeno)imidazole4-carboxamide (NSC 45388) and the 3,3-bis(2-chloroethyl) derivative (NSC 82196) was studied in vitro in Ll210 cells and in drug-resistant sublines. Uptake of both compounds was temperature sensitive and apparently nonsaturable. Accumulated NSC 45388 could be removed from the cells by brief suspension in buffer at 37°.In contrast, accumulated NSC 82 196...

The structure of a discharge across a magnetic field in a dusty plasma is analysed. The dust macroparticles are negatively charged, but are unmagnetized because of their high mass. The electrons are highly magnetized, and the ions have intermediate magnetization. This results in different transport rates of the different species across the magnetic field. Depending on the size of the magnetic f...

Remobilisation of non-structural carbohydrates (NSC) from leaves and stems and unloading into developing grains are essential for yield formation of rice. In present study, three recombinant inbred lines of rice, R91, R156 and R201 have been tested for source-flow-sink related attributes determining the nature of NSC accumulation and translocation at two nitrogen levels in the field. Compared t...

NSC 314622 was found to have a cytotoxicity profile comparable to the topoisomerase I (top1) inhibitors camptothecin (CPT) and saintopin in the National Cancer Institute In Vitro Anticancer Drug Discovery Screen using the COMPARE analysis. In vitro data showed that NSC 314622 induced DNA cleavage in the presence of top1 at micromolar concentrations. Cleavage specificity was different from CPT i...

Abstract The aim of the current study is to test how psychological distress mediates associations between neighborhood social cohesion (NSC) and cognitive performance including episodic memory, semantic verbal fluency, fluid reasoning, numeracy in older adults. Nine multiple regressions were used analyze NSC performance, distress, respectively based on data from 4922 adults with a mean age 66.5...

BACKGROUND The transplantation of neural stem cells (NSCs) has been accepted as a promising therapeutic strategy for central nervous system disorders. However, the beneficial effect of NSC transplantation upon functional recovery is limited due to the unfavorable microenvironment (niche) at the site of trauma or degenerative disease in the brain. Combination of transplantation of NSCs with neur...

It is widely accepted that a tight coordination between carbon (C) utilization in the sink and C assimilation metabolism source exists higher plants. However, much of our current understanding based on research from herbaceous plants, where interaction less sophisticated compared to woody perennials with significant presence. Apple (Malus x domestica Borkh.) good representative latter category,...