The accurate management of testicular germ cell tumors (TGCTs) depends on identifying the individual histological tumor components. Currently available data protein expression in TGCTs are limited. human atlas (HPA) is a comprehensive resource presenting and localization proteins across tissue types diseases. In this study, we have compared from HPA with our in-house immunohistochemistry core T...

We investigated a case of spontaneous malignant T-cell lymphoma observed in a 19-week-old male Crl:CD (SD) rat. The rat showed paralysis beginning 1 week before euthanasia. Hematological examination revealed marked lymphocytosis without distinct atypia. Macroscopically, hepatosplenomegaly and partial atrophy of the thoracic spinal cord were observed. Microscopically, neoplastic cells infiltrate...

Merkel cell carcinoma is a rare, rapidly progressive, aggressive skin tumor with frequent metastasis and high mortality. The disease multifactorial pathology resulting from the interaction of endogenous exogenous risk factors. Timely detection important in management prognosis patient, because often associated other neoplastic processes not only but also organs. This article presents clinical c...

Sarcomatoid carcinoma is a type of spindle cell neoplasm. These varieties neoplasms comprise diverse collection benign and malignant neoplasms. carcinoma, also known by various other names such as Spindle Lane’s tumor, to name few, an exceedingly rare aggressive variant squamous 3, 7, 8 The variation in its nomenclature reflects the divergent interpretation sarcomatoid component reactive or neo...

Low frequency ultrasound in the 20 to 60 kHz range is a novel physical modality by which to induce selective cell lysis and death in neoplastic cells. In addition, this method can be used in combination with specialized agents known as sonosensitizers to increase the extent of preferential damage exerted by ultrasound against neoplastic cells, an approach referred to as sonodynamic therapy (SDT...

In the spectrum of diffuse large B-cell lymphomas (DLBCL), both T-cell/histiocyte-rich large B-cell lymphoma (TCHRBCL) and most lymphomatoid granulomatosis (LG) cases are characterized by the relative rarity of the neoplastic B-cell population, with respect to the overwhelming non-neoplastic counterpart of T cells or histiocytes. Here we report a case of aggressive B-cell lymphoma with unusual ...

Five cases of anaplastic oligodendrogliomas containing numerous GFAP-positive cells have been analysed by electron microscopy to establish the fine structural characteristics of neoplastic cells. Ultrastructurally, all tumours have revealed monotonous appearance typical of oligodendrogliomas, however some structural variability, particularly with reference to astrocytic differentiation, has bee...