Three dedicated approaches to the calculation of the risk-adjusted net present value (rNPV) in drug discovery projects under different assumptions are suggested. The probability of finding a candidate drug suitable for clinical development and the time to the initiation of the clinical development is assumed to be flexible in contrast to the previously used models. The rNPV of the post-discover...

When countries attempt to stabilize annual inflation rates that are greater than 40 percent, the domestic stock market appreciates by 24 percent on average. The present value of the long-run benefits to shareholders of reducing high inflation outweighs the present value of the short-run costs. In contrast, the average market response is economically weak and statistically insignificant if the p...

Decision making has always been a difficult process, based on various combinations if objectivity (when scientific tools were used) and subjectivity (considering that decisions are finally made by people, with their strengths and weaknesses). The IT revolution has also reached the areas of management and decision making, helping managers make better and more informed decisions by providing them...

The credit-driven housing net worth channel has been identified as a determinant of the sharp drop in US employment between 2007 and 2009. We examine impact this on labour market EU using panel data for 20 countries covering period 1996 to 2017. This saw substantial changes both credit provision performance EU. full sample results show wealth having significant influence total its traded non-tr...