نتایج جستجو برای: neuregulin 3

تعداد نتایج: 1812651  

2009
Dawei Li Guang He Yifeng Xu Yun Duan Niufan Gu Xingwang Li Yongyong Shi Wei Qin Guoyin Feng Lin He

ERBB3 (v-erb-b2 erythroblastic leukemia viral oncogene homolog 3), encoding a receptor of neuregulin-1 (NRG1), has been considered a functional candidate gene for schizophrenia susceptibility. In order to investigate a relationship between ERBB3 gene and schizophrenia in the Chinese population, case-control and family-based studies were carried out in 470 cases matched by controls, and in 532 f...

Journal: :Psychiatry research 2013
Han Chern Loh Pek Yee Tang Shiau Foon Tee Tze Jen Chow Chee Yen Choong Shen Yang Lim Hoi Sen Yong

Neuregulin-1 is widely investigated due to its hypothesised association with schizophrenia. Single-nucleotide polymorphisms rs764059, rs2954041 and rs3924999 were investigated (417 patients with schizophrenia and 429 controls). We failed to demonstrate a significant association between rs2954041 and rs3924999 with schizophrenia in the three ethnic groups studied (Malay, Chinese, and Indian), wh...

Journal: :Diabetes 2007
Carles Cantó Sara Pich José C Paz Rosario Sanches Vicente Martínez Meritxell Orpinell Manuel Palacín Antonio Zorzano Anna Gumà

OBJECTIVE Neuregulins are growth factors that are essential for myogenesis and regulate muscle metabolism. The addition of a recombinant neuregulin-1 isoform, heregulin-beta1(177-244) (Hrg), containing 3 nmol/l of the bioactive epidermal growth factor-like domain, to developing L6E9 myocytes has acute and chronic effects on glucose uptake and enhances myogenesis. Here, we studied the metabolic ...

Journal: :Advances in anatomy, embryology, and cell biology 2007
Stefan Britsch

Neuregulins (NRGs) comprise a large family of EGF-like signaling molecules involved in cell-cell communication during development and disease. The neuregulin family of ligands has four members: NRG1, NRG2, NRG3, and NRG4. Relatively little is known about the biological functions of the NRG2, 3, and 4 proteins. In contrast, the NRG1 proteins have been demonstrated to play important roles during ...

Journal: :Circulation Research 1999

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