signs of neuroma with chaotic nerve regeneration (multidirectional axonal regrowth confirmed by histology) extending from the proximal stump as early as 4 weeks. At 5 weeks, axons grew through the entirety of the 0.5 cm ANAs, with neuroma formation extending beyond the grafts. In the 2.5 and 5.0 cm ANAs, robust axonal regeneration was demonstrated in the proximal portions of the grafts with a g...

AIM To analyse the risk factors involved in the development of ocular complications after acoustic neuroma resection, in particular corneal complications and visual loss, and to identify measures that may reduce these. METHODS 62 patients who underwent surgery for acoustic neuroma had a standardised ophthalmic examination and retrospective case note review. RESULTS At final review (mean 37....

Nonfilling of the normal internal auditory canal on computed tomographic (CT) gas cisternography was observed in seven (11%) of 62 cases in a retrospective study of three series of gas cisternograms. The meatal surface of the fluid-filled canal was convex and pointed, simulating a small acoustic neuroma. A meniscus effect at the gas-cerebrospinal fluid interface was considered the probable caus...

Metatarsalgia is a condition defined as a compression syndrome mechanically induced by intrinsic and extrinsic biomechanical factors that result in sharp pain, paresthesia and in some cases numbness of the forefoot. Metatarsalgia is often referred to as a symptom, rather than as a specific disease. Common causes of metatarsalgia include neuroma between the toes (also known as Morton’s neuroma),...

BACKGROUND AND OBJECTIVE Morton neuroma is a common cause of metatarsalgia of neuropathic origin. Systematic reviews suggest that insufficient studies have been performed on the efficacy of the different treatments available. OnabotulinumtoxinA has shown a degree of usefulness in other conditions associated with neuropathic pain. The aim of this study was to investigate the therapeutic potentia...

BACKGROUND A traumatic neuroma is not a true neoplasm but a reactive proliferation of neural tissue that commonly occurs after the transection or damage of a nerve bundle. Traumatic neuromas are rare in the oral region and usually occur as a solitary nodule of the mental foramen, lower lip, or tongue. This is the first report of a diffuse traumatic neuroma of the palate. CASE PRESENTATION A 3...

OBJECTIVES The rapid increase of mobile phone use has increased public concern about its possible health effects in Japan, where the mobile phone system is unique in the characteristics of its signal transmission. To examine the relation between mobile phone use and acoustic neuroma, a case-control study was initiated. METHODS The study followed the common, core protocol of the international ...

INTRODUCTION Acoustic neuroma usually presents as an unilateral tumor, seldom - bilateral and rarely in coexistence with other central nervous system neoplasms. The following paper reports such a case of a 21-year-old male patient presented with sudden deafness in left ear accompanied with tinnitus and vertigo. Symptoms started 4 weeks prior hospitalization. Their aggravation has been observed ...

The aim of this study was to assess the clinical effectiveness of ultrasound guided injection in the management of Morton's Metatarsalgia. Patients clinically diagnosed with interdigital Morton's neuroma were treated with ultrasound guided injection of local anaesthetic and steroid. Fifty four patients were available for follow-up, and all had detailed telephone questionnaires completed. These ...

BACKGROUND Laminins are extracellular matrix proteins that participate in endoneurial tubule formation and are important in the regeneration of nerves after injury. They act as scaffolds to guide nerves to distal targets and play a key role in neurite outgrowth. Because there is evidence that laminin architecture affects nerve regeneration, we evaluated endoneurial tubules by examining the lami...