Breast conserving surgery (BCS) with following external beam radiation therapy (EBRT) of the conserved breast has become widely accepted in the last decades for the treatment of early invasive breast cancer. The standard technique of EBRT after BCS is to treat the whole breast up to a total dose of 42.5 to 50 Gy. An additional dose is given to treated volume as a boost to a portion of the breas...

Pediatric soft-tissue sarcomas are managed with a multimodality treatment program that includes surgery, chemotherapy, and external-beam radiotherapy (teletherapy). The use of teletherapy in young children can result in significant long-term toxicities (especially growth retardation of bones and organs). Brachytherapy, if feasible, is an attractive alternative for the treatment of pediatric sof...

background: one of the main causes of induction of secondary cancer in radiation therapy is neutron contamination received by patients during treatment. objective: in the present study the impact of wedge and block on neutron contamination production is investigated. the evaluations are conducted for a 15 mv siemens primus linear accelerator.  methods: simulations were performed using mcnpx mon...

Objective: In locally advanced cervical cancer, the management consists of external beam radiotherapy and brachytherapy. The impact of intracavitary brachytherapy versus interstitial brachytherapy on local tumor control, survival and complications were prospectively investigated in this study. Methods: A total of 60 patients with stage IIB, IIIB cervical cancer were treated using a combination ...

The biological rationale for the use of brachytherapy, which is undergoing a significant resurgence in the United States, is reviewed with emphasis on low dose rate (LDR brachytherapy). Some of the newer alternatives that have recently been developed, such as pulsed dose rate (PDR) brachytherapy, are discussed.

Rationale: brachytherapy is administered in the treatment of patients with locally advanced cervical cancer following chemoradiotherapy. Lack of local anatomy evaluation prior to this procedure might lead to the selection of an inappropriate brachytherapy applicator, increasing the risk of side effects (e.g. uterus perforation, painful procedure ...). Objective: To assess the movement of the ut...

Introduction: Neutron contamination is very harmful for the patients receiving radiation therapy due to the high relative biological effect of neutrons. Medical linear accelerators head are made up of materials with high atomic numbers, and High-energy photons interaction with heavy materials can produce neutron contamination. In this study, neutron equivalent dose, neutron spe...

PURPOSE Permanent prostate brachytherapy has emerged as a standard of care treatment for approximately 50,000 men annually who present with clinically localized prostate cancer. The purpose of this review was to provide clarification on the appropriateness criteria and management considerations for the treatment of prostate cancer with permanent prostate brachytherapy. METHODS Panel members w...