BACKGROUND Ridge preservation was developed as a therapy to prevent severe bone resorption after tooth extraction. The purpose of this study is to determine if there is any difference in the amount of new bone formation ≈3 months after extraction and ridge preservation compared to that after ≈6 months. METHODS Minimally traumatic extraction with ridge preservation using mineralized human bone...

BACKGROUND Recombinant human bone morphogenetic proteins (rhBMPs) have been widely used in regenerative therapies to promote bone formation. The production of rhBMPs using bacterial systems such as Escherichia coli (E. coli) is estimated to facilitate clinical applications by lowering the cost without compromising biological activity. In clinical practice, rhBMP-2 and osteoconductive carriers (...

Objectives- To assess the ectopic bone formation in canine masseter muscle following the implantation of the natural bovine bone minerals (NBM) loaded with canine mesenchymal stem cells (MSCs).Design- Experimental study.Animals- four mongrel dogs.Procedures- Tripotent MSCs isolated from the canine bone marrow were loaded onto the NBM sponges and allowed to adhere. The cell-loaded scaffolds were...

background: alveolar ridge preservation could be performed immediately following tooth extraction to limit dimensional changes of alveolar process due to bone resorption. the aim of this study was to compare the clinical and histologic outcomes of socket preservation using two different graft materials; deproteinized bovine bone mineral (dbbm) and demineralized freeze‑dried bone allograft (dfdb...

the objective of this study was to evaluate the effect of accell connexus(®) on the quality and rate of healing in experimental defects of rabbit calvarium compared to bio-oss®.twelve 2.5-3.5 kg weighing new zealand white rabbits were used. three defects (3×6 mm) were created in the cranium of the animals subsequently filled with accell connexus(®), bio-oss® or served as controls. the animals w...