Homologous recombination is essential for repair of DNA double-strand breaks. Central to this process is a family of recombinases, including archeal RadA and human RAD51, which form nucleoprotein filaments on damaged single-stranded DNA ends and facilitate their ATP-dependent repair. ATP binding and hydrolysis are dependent on the formation of a nucleoprotein filament comprising RadA/RAD51 and ...

We investigated continuous profiles and within-day variations of some metabolites and hormones in four nonpregnant, nonlactating cows fed hay-based diets in two equal meals. Diets supplied either too much or too little N (approximately 1.3 or .8 times the maintenance requirements) and NE1 (approximately 1.2 or .8 times). Continuous collection of ruminal liquor, blood, and urine samples was perf...

Studies of the chemical alterations in muscle, associated with its activity, have been well summarized by Eggleton1", Meyerhof97, and Milroy"'0. Such summaries naturally include a discussion of only those substances which have been shown to take part in the metabolic changes. As the first demonstration of chemical change with muscle activity concerned the change of glycogen to lactic acid, it w...

The effects of nitrogenous (inorganic) fertilisers, organic manures and blue-green algae (BGA) biofertiliser on mosquito populations (Diptera: Culicidae) were studied in rice fields of Madurai, Tamil Nadu, south India, with particular attention to Culex vishnui Theobald, Cx. pseudovishnui Colless and Cx. tritaeniorhynchus Giles, the vectors of Japanese encephalitis (JE). The application of urea...

The idea of the use of yeast as a source of food protein for man and the higher.animals is not a new one; it has, however, been given renewed emphasis by the exigencies of the food situation during the war. Yeast is a highly nitrogenous by-product of the fermentation industries which heretofore has been largely wasted. It also presents the possibility of a synthetic production of protein from e...

● Dietary therapy is a key element in the conservative medical management of chronic renal failure (CRF) in dogs and cats. ● Appropriate dietary modifications can alleviate clinical signs of uremia and may help to slow progression of renal damage. ● Although the restriction of dietary protein is of clinical benefit in uremic patients, excessive protein restriction can cause protein malnutrition...

Several studies have assessed the effects of nitrogenous compounds on amphibian behavior. However, few have focused on the effects of their combination with other stressors or on the variation of the response to pollutants among populations. We analyzed the effect of nitrogenous compounds (NH(4)(+); NO(2)(-); NO(3)(-), both alone and in combination) on larval behavior (activity level and locati...

The relationship postulated between hepatic coma and hyperammonaemia implicates the gastrointestinal tract as a major source of the excess ammonia in the peripheral blood of some patients with cirrhosis (Butt and Summerskill, 1961; Chalmers, 1960; Sherlock, Summerskill, White, and Phear, 1954). Conventional therapy, comprising protein restriction, antibiotics, and enemas, is directed toward eli...