© 2017 Advanced Biomedical Research | Published by Wolters Kluwer Medknow Sir, Shirani et al. recently reported an article entitled, “Nocardial brain abscess in a patient with pulmonary alveolar proteinosis” (DOI: 10.4103/2277-9175.164004).[1] The genus Nocardia is a Gram-positive aerobic, partially acid-fast, and fi lamentous bacterium that causes nocardial infections (nocardiosis) in human. T...

The patient was a 71-year-old man. Two months after using prednisolone at a dose of 80 mg/day for the treatment of drug-induced interstitial pneumonia induced by chemotherapy following lung cancer surgery, his chest x-ray fi lm showed cavitary shadows, and Nocardia farcinica was detected from subcutaneous abscess, sputum, urine, and blood cultures. Thus, disseminated nocardiosis involving multi...

In this paper a disseminated persistent Nocardia cyriacigeorgica infection in an immunocompetent patient is described. The patient's long-term treatment, as well as its implications for managing similar cases in the future, is emphasized. Presenting with high fever, multiple nodules, and ulcerative cutaneous lesions of body sites, the patient was treated with various antimicrobials. Under combi...

Nocardiosis is a rare human infection due to ubiquitous soil born gram-positive, filametous aerobic bacteria. First signs are frequently cutaneous either as part of systemic infection disseminated to the skin, or as primary cutaneous inoculation. An 88 years old man presented with a 3-day history of red papules and pustules with pain on his forehead. The combination of the unusual clinical pres...

Nocardiosis is an uncommon bacterial gram-positive infection caused by aerobic actinomycetes in the genus Nocardia. Nocardiosis is typically regarded as an opportunistic infection with approximately two-thirds of infected patients being immunocompromised. In this case report we describe a 45-year-old female who presented with a right thigh abscess. She had been taking high-dose prednisolone and...

A novel therapeutic approach for Nocardia infections is presented. We report the successful treatment of lymphocutaneous nocardiosis with a three-drug combination in an immunocompromised patient with in vitro susceptibility testing used to guide therapy. New therapeutic options are required in some patients due to their failure to respond to the treatment of choice, trimethoprim-sulfamethoxazol...

Nocardiosis is an uncommon infection that occurs primarily in the immunocompromised patients, especially in patients with defective cell-mediated immunity [2]. Less commonly it may also be encountered in immunocompetent hosts. However, its incidence is rising probably due to the advent of improved and advanced laboratory detection methods and also due to the growing number of immunosuppressed p...

cutaneous inoculation. Primary cutaneous nocardiosis is more common, with incidence rates ranging from 5% to 24% in various countries like India, UK, and Spain [10-12]. A major problem is correct identification, as clinical presentation is not peculiar as well as histological findings, suggestive of an infective process, but not able to detect the microorganisms, unless a tissue culture has bee...

a b s t r a c t a few case reports of coinfections with nocardia and mycobacterium tuberculosis (tb) have previously been published in the literature. we report on a case of concomitant pulmonary nocardiosis and tuberculosis, in a recently diagnosed 55-year-old woman, with rheumatoid arthritis, who had been taking a short course of a low dose corticosteroid. the patient was treated with a combi...