a reliable method is described for rapid proliferation of axillary shoots from nodal segment of mature field-grown aromatic and medicinal plant vitex negundo through in vitro culture. of different concentrations of n6-benzyladenine (ba) evaluated as supplements to murahige and skoog (ms) medium, ba at 1mg/l was effective in enhancing bud break and shoot regeneration. response of explants was al...

Cripto-1, a co-receptor for Nodal, can activate Nodal-dependent and Nodal-independent signaling pathways. In this study we have investigated whether Cripto-1 mutants, that fail to activate a Nodal-dependent signaling pathway, are capable to activate a Nodal-independent signaling pathway in mammary epithelial cells. Cripto-1 mutants expressed in EpH4 mouse mammary epithelial cells are fully func...

Türkiye'nin endemik bitki türlerinden biri olan “Mor Mercan” ad?yla bilinen Origanum sipyleum L., Lamiaceae familyas?ndan olup yüksek t?bbi ve aromatik de?ere sahiptir. türlerinin antikanserojenik, sitotoksik, antibakteriyel, antidiyabetik, antifungal, antiviral, insektisidal etkilerinin oldu?unu çe?itli bilimsel çal??malar gösterilmi?tir. Bununla birlikte, genetik kaynaklar?n korunmas?nda de?e...

Nodal, an important embryonic morphogen, has been reported to modulate tumorigenesis. Epithelial-mesenchymal transition (EMT) plays an important role in cancer metastasis. We have previously reported that recombinant Nodal treatment can promote melanoma undergoing EMT, but the effects of endogenous Nodal on EMT are still unknown. Here we generated both Nodal-overexpression and -knockdown stable...

introduction: the aim of the present study was to determine direct effects of no modulation on protective electrophysiological properties of atrioventricular node (av node) in the experimental model of af in rabbit. methods: isolated perfused rabbit av nodal preparations were used in two groups. in the first group (n=7), lname (50μm) was applied. in the second group (n=12), different concentrat...

The paper deals with a technique of sensitivity calculation in linear hybrid networks containing elements with both lumped and distributed parameters when the multiconductor transmission lines (MTL) are considered as the distributed parts. The technique utilizes the modified nodal analysis (MNA) method to do overall description of the network enabling determining sensitivities with respect to b...

Recently proposed methods for ordering sparse symmetric matrices are discussed and their performance is compared with that of the Minimum Degree and the Minimum Local Fill algorithms. It is shown that these methods applied to symmetrized modified nodal analysis matrices yield orderings significantly better than those obtained from the Minimum Degree and Minimum Local Fill algorithms, in some ca...

The Transforming Growth Factor-ß (TGFß) family ligand Nodal is an essential embryonic morphogen that is associated with progression of breast and other cancers. It has therefore been suggested that Nodal inhibitors could be used to treat breast cancers where Nodal plays a defined role. As secreted antagonists, such as Cerberus, tightly regulate Nodal signaling during embryonic development, we u...

An inverse nodal problem has first been studied for the Sturm-Liouville equation with one turning point. The asymptotic representation of the corresponding eigenfunctions of the eigenvalues has been investigated and an asymptotic of the nodal points is obtained. For this problem, we give a reconstruction formula for the potential function. Furthermore, numerical examples have been established a...