Isothermal calorimetric titration of 18-crown-6 ether with BaCl2 in pure aqueous solution over the temperature range 7-40 degrees C gives precise binding constants and enthalpy changes. Nonlinear least-squares fitting of the binding constants to the integrated van't Hoff equation, including a temperature-independent change in heat capacity, leads to van't Hoff enthalpies that differ significant...

1. Carbon dioxide titration curves were determined in vivo in dog and man at various degrees of acute non-respiratory acidaemia and alkalaemia. 2. The slope of the CO2 titration curve (delta log Pco2/delta pH) was found to increase with the severity of the acute non-respiratory alkalaemia the slope (delta log Pco2/delta pH) tended towards unity. 3. A simple scheme based on the CO2 titration cur...

The study of 1:1 cyclodextrin inclusion compounds by isothermal titration calorimetry was explored in a theoretical and experimental point of view to compare the efficiency of conventional and non-conventional experiments. All direct and competitive protocols were described and evaluated in terms of accuracy on both binding constant and inclusion enthalpy. Significant improvement in the calorim...

A number of Sm (III) selective membranes of varying compositions using tin (IV) boratophosphate as electroactive material were prepared. Polyvinyl chloride, polystyrene and epoxy resin were used as binding materials. Membrane having composition of 40% exchanger and 60% epoxy resin exhibited best performance. This membrane worked well over a wide concentration range of 1x10M to 1x10 M of samariu...

to nalidixic acid. Chemically, PFM, is 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-peperazinyl)-4-oxo-3-quinolinecarboxylic acid, methane sulfonate dihydrate (Fig. 1). It is an antibacterial drug, which is highly effective against both Gram-negative and Gram-positive pathogens that are resistant to other antibacterials (1). The therapeutic importance of PFM has necessitated the development of an...

This study on potentiometric titration of polyprotic acids and bases using a glass electrode is a continuation of our paper (Maslarska V., Tencheva J., Budevsky O., Anal. Bioanal. Chem., 375, 217 (2003)) [1]. The derived earlier theoretical equation was found to fit well the experimental data. A commercial software was applied and main attention was paid to the analytical result rather than to ...

A direct potentiometric titration method was applied for determination of Ranitidine Hydrochloride. The method is based on the treatment of the primary data with nonlinear regression procedure using commercial software. A general formula valid for every type of acid base titration, derived before is used as a direct input. The acid-base constants of N, N dimethyl-5 [2-(1-methylamine-2-nitroviny...

In 1946 Kolthoff and Harris devised a method of titrating mercaptans in aqueous alcoholic solution with silver nitrate. They used a rotating platinum electrode with suitable current measuring equipment to locate the titration end-point. Benesch and Benesch (1948) applied this technique to the determination of sulphydryl groups in serum protein, and Weissman, Schoenbach, and Armistead (1950) use...

A photo/thermal-switchable supramolecular nanoparticles assembly has been constructed based on an inclusion complex between anionic pillar[5]arene 2C-WP5A and azobenzene derivative Azo-py-OMe (G). The novel anionic pillar[5]arene-based host-guest inclusion complexation was investigated by the 1H NMR titration, 2D ROESY and isothermal titration microcalorimetry (ITC) showing high association con...