Miranda-Filho et al. in their recently published paper entitled “Cancers of the brain and CNS: global patterns and trends in incidence” provided a global status report of the geographic and temporal variations in the incidence of brain and CNS cancers in different countries across continents worldwide. While the authors confirm the role of genetic risk factors and ionizing radiation exposur...

Alzheimer’s disease, the most common type of dementia and a progressive neurode-generative disease, occurs when the nerve cells in the brain die. Although there are medications that can help delay the development of Alzheimer’s disease, there is cur-rently no cure for this disease. Exposure to ionizing and non-ionizing radiation may cause adverse health effects such as cancer. Looking at th...

Traditionally, non-cancer diseases are not considered as health risks following exposure to low doses of ionizing radiation. Indeed, non-cancer diseases are classified as deterministic tissue reactions, which are characterized by a threshold dose. It is judged that below an absorbed dose of 100 mGy, no clinically relevant tissue damage occurs, forming the basis for the current radiation protect...

These authors investigated the potential link between pilots’ exposure to non-ionizing radiation and the incidence of cancer. Mortality statistics were reviewed for 2,740 pilots using standardized mortality and incidence ratios (SMR) & (SIR). Rates were contrasted with a non-exposed referent population. The preferred relative risk model for radiation-induced nonchronic lymphoid leukemia (Beir V...

introduction: ionizing radiations are the hazardous agents in the workplace and all forms of ionizing radiation produce some type of injuries. awareness of application of protection guidelines and knowledge of the principles of radiation protection can play an important role in health of employees. survey of radiation employee’s levels of awareness and practical behavior is essential and should...

Ionizing radiation-induced formation of genomic DNA damage can be modulated by nearby chemical species such as heavy metal ions, which can lead to non-linear dose response. To investigate this phenomenon, we studied cell survival and formation of 8-hydroxyguanine (8-OHG) base modifications and double strand breaks (DSB) caused by combined action of cadmium (Cd) and gamma radiation in cultured m...

radiography is one of the most valuable diagnostic tools used in comprehensive dental care. although there is no safe level of radiation exposure, the possible risk associated with exposure to radiation, must be elucidated. to date, a variety of assays have been proposed to assess the mutagenic potential of genotoxicants; however, these methods are typically laborious and time consuming. the ai...

conclusions the increasing cell toxicity, apoptosis-inducing effects and decreasing telomerase activity may play an important role in the valproic acid and radiation mechanism. the current survey suggested that it is likely beneficial to combine valproic acid and gamma radiation to treat breast cancer. results combination of valproic acid and gamma radiation increased significantly cell toxicit...

background: the aim of the study was to analyze the effective dose record of occupationally exposed radiation workers at bahawalpur institute of nuclear medicine and oncology department. materials and methods: annual effective doses of occupationally exposed workers were measured by film badge dosimetry by sending the dosimeters to radiation dosimetry laboratory (rdl), pakistan institute of nuc...

the protective effects of rheum tanguticum polysaccharide 1 (rtp1), which is extracted from the chinese traditional medicine rheum tanguticum, on radiation-induced intestinal mucosal injury was investigated. rat intestinal crypt epithelial cells (iec-6 cells) and sprague-dawley rats were each divided into control, irradiated and rtp1-pretreated irradiated groups. after irradiation, cell surviva...