conclusions synbiotic supplementation may improve lipid profile and body composition in patients with nafld and might be useful in prevention of the disease progression. methods eighty patients with nafld participated in this randomized, double-blind, placebo-controlled clinical trial (from march to july 2014) in iran. based on ast and alt as main variables of the study, 34 patients were requir...

We compared the relationships of alcoholic fatty liver and nonalcoholic fatty liver with hypertension, diabetes mellitus, and dyslipidemia. Using a nationwide Japanese survey, we collected data on subjects with biopsy-proven alcoholic fatty liver or nonalcoholic fatty liver. Multiple logistic regression analysis was performed to determine whether alcoholic fatty liver and nonalcoholic fatty liv...

Hepatic steatosis (commonly called fatty liver) is mostly an asymptomatic liver disease, which is diagnosed mostly as a part of an unrelated condition. It was considered to be a benign consequence of chronic alcohol intake. In absence of alcohol intake of >20 g/day, it is termed as nonalcoholic fatty liver disease (NAFLD). Nonalcoholic fatty liver disease consists of accumulation of fat within ...

Background and objectivesMethylenetetrahydrofolate Reductase (MTHFR) is the critical enzyme in folate 1-carbon metabolism. MTHFR polymorphisms may result increased homocysteine levels, be associated with abnormal lipid metabolism liver. This study aims to explore association between gene of rs1801131 rs1801133 susceptibility nonalcoholic fatty liver disease (NAFLD) coronary artery (CAD).

results the relative expression of mtdna copy number was 3.7 fold higher in nafld patients than healthy controls (p < 0.0001). the results remained significant after adjustment for age, bmi, and gender (p = 0.02). in addition, the mtdna copy number was 4.3 (p < 0.0001) and 3.2-fold (p < 0.0001) higher in nonalcoholic fatty liver (nafl) and non-alcoholic steatohepatitis (nash) patients than heal...

conclusions saturated fatty acids (sfas) served as a potential ligand for tlr4 and activated tlr4 signaling pathway, which might be involved in the pathogenesis. thus, sfas can accelerate the mechanism of inhibiting hbv replication in chb with nafld. objectives this study aimed to investigate whether the tlr4-mediated innate immunity stimulates the pathogenesis of chb in patients with nafld and...