normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 colorectal cancer is classified in to three forms: sporadic (70-75%), familial (20-25%) and hereditary (5-10%). hereditary colorectal cancer syndromes classified into two different subtypes: polyposis and non polyposis. familial adenomatous polyposis (fap; omim #175100) is the most common polyposis syndrome, account for <1...

To date, only a few randomized clinical trials (RCTs) have investigated the effects of omega-3 fatty acids (FA) on Alzheimer's disease (AD). Some of these studies demonstrated that patients with very mild AD or mild cognitive impairment benefit from omega-3 FA treatment, but none showed significant improvements in cognitive function in patients with moderate or advanced AD. All these RCTs had a...

objective mitochondrial dna (mtdna) is considered a candidate modifier factor for neuro-degenerative disorders. the most common type of ataxia is friedreich's ataxia (fa). the aim of this study was to investigate different parts of mtdna in 20 iranian fa patients and 80 age-matched controls by polymerase chain reaction (pcr) and automated dna sequencing methods to find any probable point mutati...

introduction: allogeneic hematopoietic cell transplantation (hsct) is the only therapeutic modality capable of correcting the hematologic manifestations of fanconi anemia (fa). the development  of well  tolerated,  immunosuppressive  conditioning  regimens  for fa patients  undergoing hsct has proven to be a rather challenging task for hematologists. methods: we analyzed the outcome of 30 fa pa...

herpes simplex esophagitis (hse) has rarely been reported in immunocom­petent individuals. in a search of medline until october 2012, we found only one case of hse in a pregnant female. we present the first case of hse in a healthy 36-year-old female at 27 weeks gestation who recovered without an­tiviral therapy. normal 0 false false false en-us x-none fa

In this paper, we presented the experimental discussion of samples recycled aggregate concrete with replacement natural fine by aggregate. Three mix kinds were produced and, for each these three kinds, two levels water to blinder ratio used 0%, 10% and 20% FA. The result tests drying shrinkage compressive strength comparison mercury intrusion porosimetry (MIP), in which cumulative pore volume d...

This study aims to test the value of diffusion tensor (DT) magnetic resonance (MR) imaging and fractional anisotropy (FA) mapping in detection of early cord dysfunction due to cervical spondilotic myelopathy before myelopathy is apparent on T2 weighted MR images Methods Totally 21 patients with neurological signs and symptoms of degenerative cervical stenosis enrolled in the study. None of the ...

Fanconi anemia (FA) is a chromosome instability syndrome, characterized by progressive pancytopenia and cancer susceptibility. Other cellular features of FA cells are hypersensitivity to DNA cross-linking agents and accelerated telomere shortening. We have quantified overall genome chromosome fragility and euploidy as well as chromosomes 7 and 8 aneuploidy in peripheral blood lymphocytes from a...

Recent studies have examined and demonstrated the potential cancer chemopreventive activity of freeze-dried berries including strawberries and black raspberries. Although ellagic acid, an abundant component in these berries, has been shown to inhibit carcinogenesis both in vivo and in vitro, several studies have reported that other compounds in the berries may also contribute to the observed in...