Because of the enormous economic and social impact of cardiovascular disease in the United States, there is a need for improved noninvasive diagnosis. Cardiac MR imaging is a versatile, comprehensive technique for assessing cardiac morphology and function. With an understanding of cardiac anatomy and physiology as well as MR physical principles, cardiac MR imaging can be performed and play an i...

Initial comparisons of the results of digital subtraction angiography (DSA) and a battery of tests for noninvasive diagnosis of carotid artery disease indicate the two techniques are complementary, rather than competitive. DSA provides important morphologic information at the carotid bifurcation and siphon, but the images are sometimes difficult to interpret with precision. Noninvasive testing ...

Coronary artery anomalies (CAAs) are a rare entity but their true incidence in the general population has yet to be determined. Most CAAs are asymptomatic, but they are nevertheless the second leading cause of sudden death in apparently healthy young athletes. The new imaging methods available to cardiologists, including CT angiography and MRI, now enable noninvasive diagnosis and characterizat...

The technique of large-eddy simulation (LES) has been applied to the study of pulsatile flow through a modeled arterial stenosis. A simple stenosis model has been used that consists of a one-sided 50 percent semicircular constriction in a planar channel. The inlet volume flux is varied sinusoidally in time in a manner similar to the laminar flow simulations of Tutty (1992). LES is used to compu...

We propose a feature extraction method for noninvasive diagnosis of melanoma based on tensor decomposition of the clinical color image of skin lesion. Extracted features are elements of the core tensor in the corresponding Tucker3 model, and represent spatial-spectral profile of the lesion. In contrast to majority of methods that exploit either texture or spectral diversity of the tumor only, t...

A rapid dimethyl sulfoxide modification of an acid-fast technique was applied to direct fecal smears to monitor cryptosporidiosis in nonhuman primates. Brilliantly stained pink oocysts against a pale green background demonstrated well-preserved internal morphology and facilitated rapid, simple, noninvasive diagnosis without fluorescent or phase-contrast microscopy.

Chronic thromboembolic pulmonary hypertension is the only potentially curable form of pulmonary hypertension, assuming that surgical treatment is possible. However, there are hindrances to making a definitive, noninvasive diagnosis. We present the case of a 40-year-old female patient with idiopathic pulmonary arterial hypertension, confirmed in 1994. This patient developed thrombi in pulmonary ...

BACKGROUND Sebaceous carcinoma is notorious for masquerading clinically as other benign lesions such as chalazion. A tool to better differentiate between these two conditions would thus be desirable. PURPOSE To examine the potential application of noninvasive meibography in the differential diagnosis of chalazion and sebaceous carcinoma of the eyelid as a retrospective cross-sectional study. ...

Reflectance confocal microscopy (RCM) has seen increasing clinical application for noninvasive diagnosis of skin cancer. Identifying the location of the dermal-epidermal junction (DEJ) in the image stacks is key for effective clinical imaging. For example, one clinical imaging procedure acquires a dense stack of 0.5×0.5mm FOV images and then, after manual determination of DEJ depth, collects a ...

We report a hyperspectral imaging system to measure the reflectance spectra of real human irises with high spatial resolution. A set of ocular prosthesis was used as the control condition. Reflectance data were decorrelated by the principal-component analysis. The main conclusion is that spectral complexity of the human iris is considerable: between 9 and 11 principal components are necessary t...