Estimates of the density spectrum of the macular pigment (Wyszecki G, Stiles WS. Color Science: Concepts and Methods, Quantitative Data and Formulas. 1st ed. New York: Wiley, 1967); (Vos JJ. Literature review of human macular absorption in the visible and its consequences for the cone receptor primaries. Institute for Perception. Soesterberg, The Netherlands, 1972) are partially based on the di...

PURPOSE Occult macular dystrophy (OMD) is an inherited retinal disease characterized by a progressive decrease of vision and appearance of normal fundus. To determine the pathologic features of OMD, we investigated the alternation of the photoreceptors using quantitative image analysis. METHODS We studied 22 eyes of 11 OMD patients. Three of them had a mutation (R45W) in RP1L1. The relative i...

PURPOSE To define the nature and estimate the molecular weight range of soluble endogenous retinal trophic activities on cone photoreceptor survival in two models of cone degeneration. METHODS Diffusible factors from dissociated retinal cell cultures of 8-day normal-sighted (C57BL/6J) mice were tested for cone-survival-promoting activity by two approaches and by using two independent photorec...

PURPOSE Oligocone trichromacy (OT) is an unusual cone dysfunction syndrome characterized by reduced visual acuity, mild photophobia, reduced amplitude of the cone electroretinogram with normal rod responses, normal fundus appearance, and normal or near-normal color vision. It has been proposed that these patients have a reduced number of normal functioning cones (oligocone). This paper has soug...

and Applied Analysis 3 Example 1.2. The vector spaceC1 0, 1 consisting of all continuously differentiable real-valued functions on 0, 1 equipped with the modular ρ defined by ρ x max t∈ 0,1 |x t | max t∈ 0,1 ∣ ∣x′ t ∣ ∣, ( x ∈ C1 0, 1 ) 1.7 constitutes a complete modular space. The subset P { x ∈ C1 0, 1 : x t ≥ 0, ∀t ∈ 0, 1 } 1.8 is a unital cone in C1 0, 1 with unit 1. The cone P is not norma...

Here H = div (n) is the mean curvature, n is the outward unit normal, x is the position vector and 〈, 〉 denotes the Euclidean inner product. One reason that selfshrinking solutions to the mean curvature flow are particularly interesting is that they provide singularity models of the flow; see [20, 21], [24] and [46]. Throughout, O is the origin of R; BR denotes the open ball in R n+1 centered a...

Cone electroretinograms were elicited with a full-field red flash after-45 min of dark adaptation from 16 patients with retinitis pigmentosa and from 17 normal subjects. The average latency and implicit time of the cone a-waves recorded from the patients were each significantly delayed (p less than 0.005) compared with the average normal values. In addition, the patient's waveforms typically sh...

Abstract Let ? be a proper open cone in real Banach space V . We show that the tube domain V ? i ? ? {V\oplus i\Omega} over is biholomorphic to bounded symmetric if and only normal linearly homogeneous Finsler cone, which equiva...

Citation: Bruce KS, Harmening WM, Langston BR, Tuten WS, Roorda A, Sincich LC. Normal perceptual sensitivity arising from weakly reflective cone photoreceptors. Invest Ophthalmol Vis Sci. 2015;56:4431–4438. DOI:10.1167/iovs.15-16547 PURPOSE. To determine the light sensitivity of poorly reflective cones observed in retinas of normal subjects, and to establish a relationship between cone reflecti...