BACKGROUND There is a growing body of evidence that testicular function has decreased rapidly over the last 50 years. However, much less is known about corresponding trends in ovarian function. Herein, we examine the temporal changes in ovarian function in a large sample of infertile patients from the Czech Republic over a period of 14 years. METHODS In a retrospective study, we analysed a la...

Background & Aims: Serum progesterone level (as early as 4 weeks gestation) reflects the relation between embryo and corpus luteum. The purpose of the present study was to compare serum progesterone level on day 14 after embryo transfer among 3 groups of patients undergoing intracytoplasmic sperm injection (ICSI) cycles; normal pregnancy (viable intrauterine pregnancy), abnormal pregnancy (misc...

In aging humans, night levels of melatonin (MEL) decline progressively. Also thyroid and gonadal functions decline during aging while gonadotropins (luteotropic hormone (LH) and follicle stimulating hormone (FSH)) steadily increase. A desynchronization of pineal circadian cyclicity as expressed by the progressive decrease of the MEL night peak may be permissively linked to the onset and progres...

BACKGROUND The present study addresses the issue of biological ageing of the oocyte (as indicated by basal serum FSH levels) versus chronological ageing. METHODS 1019 infertile but ovulating women were studied in their first cycle of IVF treatment. A series of logistic regression models were developed to assess statistical significance of effects of age and FSH on implantation rates and live ...

Background Precocious puberty is a common endocrine disease in children. Inappropriate activation of hypothalamic-pituitary-gonadal axis leads to the development of secondary sexual characteristics at an earlier age than normal children and causes short stature in adulthood. Objectives The aim of this study is to evaluate the preventive effects of a herbal formulation containing a mixture of ...

Plasma luteinising hormone (LH) and follicle-stimulating hormone (FSH) concentrations were measured before and after intravenous luteinising hormone-releasing hormone (LH-RH) in 33 boys with growth delay. Eighteen were prepubertal and 15 pubertal. Basal LH and FSH levels were low in both groups with mean increments after LH-RH of 3.2 +/- 0.8 U/l (mean +/- SEM) and 2.6 +/- 0.4 U/l respectively i...

background: this study was undertaken to evaluate the role of day 3 fsh/lh ratio and day 3 lh level as predictors of ivf cycle outcomes. methods: this prospective observational study was undertaken in the ivf and reproductive biology centre and lok nayak hospital, affiliated to maulana azad medical college, in new delhi, india. the study included 105 women who underwent controlled ovarian hyper...

The problem of adenomyosis is particularly relevant for patients reproductive age, as it accompanied by the significant disturbances menstrual and generative functions. article presents results studying condition hypothalamic-pituitary-ovarian system in women age with adenomyosis.The objective: to study state benign endometrial myometrial pathology.Materials methods. main group included 120 pat...

Puberty is frequently delayed in adolescent patients with chronic renal failure, due to temporarily insufficient hypothalamo-pituitary stimulation of the gonads. In these patients, basal levels of gonadotropins are normal or slightly elevated due to increased plasma half-life of luteinizing hormone (LH) and follicle stimulating hormone (FSH) [1]. However, the response to gonadotropin releasing ...