Background: The health risks of crack cocaine smoking on the oral mucosa has not been widely researched and documented. Objective: The purpose of this study was to analyze the proliferative activity of oral epithelial cells exposed to crack cocaine smoke using silver nucleolar organizer region (AgNOR) staining. Methods: Oral smears were collected from clinically normal-appearing buccal mucosa b...

The biochemical events that make colonic epithelial cells proceed along the adenoma-carcinoma sequence are not well understood. The phosphoinositol signal transduction pathway is involved in the regulation of cell growth and differentiation. To determine its role in colonic neoplasias we performed mass measurements of its second messenger sn-1,2-diacylglycerol in biopsy specimens from normal mu...

Background & Aims: Leukoplakia is the most common premalignant or potentially malignant lesion of the oral mucosa and its potentiality for malignant transformation is unpredictable. The aim of the present study was to evaluate p53 expression in normal oral epithelium, leukoplakia and oral squamous cell carcinoma. Methods: The standard Biotin streptavaidin peroxidase immunohistochemical staining...

herein, we report on a 24-year-old woman with a large well- marginated gastric mucosa-associated lymphoid tissue (malt) lymphoma. she presented with dysphagia and epigastric pain. in esophago­gastro­duodeno­scopy there was a huge bulging submucosal mass with normal appearing mucosa in the cardia in addition to a grade b gastro-esophageal reflux disease. she was treated with a proton pump inhibi...

Abstract Background MC3-R and MC5-R receptors belong to the complex melanocortin system, which has shown a strong immunomodulatory activity in several studies. Data on role of these relation inflammatory bowel disease are still missing not fully elucidated. In this observational study we wanted evaluate expression profile them colonic mucosa Crohn’s Disease Ulcerative Colitis patients both trac...