نتایج جستجو برای: normobaric hyperoxia
تعداد نتایج: 3947 فیلتر نتایج به سال:
Extracellular superoxide dismutase (EC-SOD, or SOD3) is the major extracellular antioxidant enzyme in the lung. To study the biologic role of EC-SOD in hyperoxic-induced pulmonary disease, we created transgenic (Tg) mice that specifically target overexpression of human EC-SOD (hEC-SOD) to alveolar type II and nonciliated bronchial epithelial cells. Mice heterozygous for the hEC-SOD transgene sh...
Splanchnic ischemia and reperfusion (I/R) causes tissue hypoxia that triggers local and systemic microcirculatory inflammatory responses. We evaluated the effects of hyperoxia in I/R induced by occlusion of the superior mesenteric artery (SMA) for 40 min. followed by reperfusion (120 min) in rats. Four groups were studied: a) control undergoing anesthesia only. b) Sham – undergoing all surgical...
BACKGROUND In clinical practice, oxygen is generally administered to patients with the intention of increasing oxygen delivery. Supplemental oxygen may, however, cause arterial hyperoxia, which is associated with hemodynamic alterations. We performed a systematic review and meta-analysis of the literature to determine the effect of hyperoxia on central hemodynamics and oxygen delivery in health...
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