Intractable seizures can have a devastating effect on the development of a child. In children with intractable epilepsy that is refractory to medication, surgical treatment may be needed. Magnetic resonance imaging is an essential neuroimaging tool to assist in the identification of an epileptogenic substrate. The interpretation of MR images should be done in the context of clinical knowledge o...

introduction: one of the major problems in the development of nuclear medicine images is the presence of noise. the noise level in nuclear medicine images is usually reduced by the analysis of imaging data in a fourier transform environment. the main drawback of this environment belongs to low signal to noise ratio in high frequencies because removing noise frequencies may remove data and times...

Epilepsy affects 5 to 10 per 1000 of the general population. It is the third most common neurological disorder after stroke and Alzheimer's disease. Available anti-convulsant drugs effectively control epilepsy in about 50% of the patients. Many epileptic seizures are refractory to current anti-epileptic drugs and safety of the anti-epileptic drugs has always been a concern. Herbal drugs may ser...

today, nuclear medicine has rapidly been developed so that in some cases, plays a unique role in diagnosis but unfortunalty in spite of diagnostic and therapeutic advantages, the term “nuclear” can induce worries in patients and society. in this article, base on new documents, we intend to show that this worries has no scientific basis. to produce a realistic view, regarding to radiation protec...

In 1955, the first nuclear medicine division was established in Thailand by Professor Romsai Suwannik in the Department of Radiology, Siriraj Hospil, Mahidol University in Bangkok. In 1959 four years later, the second nuclear medicine division was established in the Department of Radiology, Chulalongkorn Hospital in Bangkok. The third nuclear medicine division was started in Rajvithi Hospital i...

TAPANI TIKKAKOSKI Editor In patients with intractable epilepsy refractory to medication, surgical treatment may be needed. Magnetic resonance imaging (MRI) is an essential neuroimaging tool in assisting the identifi cation of epileptogenic lesions. MRI at 3T has been found to perform better than 1.5T in terms of image quality, detection of structural lesions, and characterization of lesions. Th...

Objective: To examine the expressions of mitochondrial translation elongation factors Tu (EF-Tumt) and Ts (EF-Tsmt) in the epileptogenic zone of patients with refractory temporal lobe epilepsy. Methods: Epileptogenic zone resection specimens were obtained from 20 patients with refractory temporal lobe epilepsy. Control samples were temporal lobe cortex tissues derived from 6 non-epileptic patie...

High-risk and refractory neuroblastomas carry poor overall survival, novel approaches must be explored to improve global outcome. With better knowledge of underlying molecular patterns growing radioligand portfolio, nuclear medicine physicians can test new strategies for disease assessment therapy. For decades, meta-iodobenzylguanidine (mIBG) has been used evaluate extent when coupled with iodi...