We examine the relationship between portfolio manager ownership, closed-end fund premiums/discounts, and future returns. Using a sample of 592 closed-end funds in 2005, representing 95% of the entire industry, we find that fund manager ownership has a positive and economically significant impact on fund premiums and future fund performance measured using both NAV and price returns. Furthermore,...

Eric Zarahn, Leeor Alon, Sophia L. Ryan, Ronald M. Lazar, Magnus-Sebastian Vry, Cornelius Weiller, Randolph S. Marshall and John W. Krakauer The Neurological Institute, New York, NY 10032, USA, Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA, Department of Neurology, University of Freiburg and Department of Neurology, Johns Hopkins Univer...

The helminth burdens of 17 springbok from 2 localities in the Transvaal and of 4 springbok from the western Cape Province were determined. Eight of the animals from the Transvaal and the 4 from the Cape Province were also examined for arthropod parasites. In all, 26 helminth species, 5 species of ixodid ticks and 4 species of lice were recovered from the springbok. Of the helminths Dictyocaulus...

John Earman and John T. Roberts advocate a challenging and radical claim regarding the semantics of laws in the special sciences: the statistical account. According to this account, a typical special science law “asserts a certain precisely defined statistical relation among well-defined variables” (Earman and Roberts 1999) and this statistical relation does not require being hedged by ceteris ...

A descending inhibitory mechanism from the periaqueductal gray (PAG) to the spinal cord through the nucleus raphe magnus (NRM) is strongly involved in endogenous analgesic system produced by acupuncture stimulation. In addition to the PAG to NRM system which descends in the medial pathway of the brain stem, the nucleus reticularis lateralis (NRL) situated in the lateral part of the brain stem i...

This is a review of research aimed at elucidating how various opiate analgesia substrates in rat brain stem interact with one another to bring about opiate analgesia. The three substrates studied are the midbrain periaqueductal grey (PAG), the bulbar nucleus raphe magnus (RM), and the bulbar nucleus reticularis paragigantocellularis (PGC). The methods used in the reviewed studies are unique in ...

In order to get a more complete picture of how labor supply is affected by economic incentives, the effects on absenteeism and not just on contracted hours should be taken into account. In particular, absenteeism due to sick leave can be considerable. In this paper we examine whether the level of sick leave compensation affects sick leave behavior. Using time-series data for Sweden spanning a l...

In rats, opioids produce analgesia in large part by their effects on two cell populations in the medullary raphe magnus (RM). To extend our mechanistic understanding of opioid analgesia to the genetically tractable mouse, we characterized behavioral reactions and RM neural responses to opioid administration. d-Ala(2), N-Me-Phe(4)-Gly(5)ol-enkephalin, a mu-opioid receptor agonist, microinjected ...

Neurons in the medullary raphe magnus (RM) that are important in the descending modulation of nociceptive transmission are classified by their response to noxious tail heat as ON, OFF, or NEUTRAL cells. Experiments in anesthetized animals demonstrate that RM ON cells facilitate and OFF cells inhibit nociceptive transmission. Yet little is known of the physiology of these cells in the unanesthet...