We administered foliar applications of 50, 100, and 200 mg L-1 selenium (Se, selenite) on turnip (Brassica rapa var. rapa Linn.) and detected the changes in the main nutrient components in fleshy roots. Results showed that the foliar application of Se (IV) significantly increased the Se content in turnip, and Se (IV) positively affected the uptake of several mineral elements, including magnesiu...

We study an optimal control problem arising from a resource allocation problem in cellular metabolism. A minimalistic model that describes the production of enzymatic vs. non-enzymatic biomass components from a single nutrient source is introduced. The basic growth modes with this model are linear growth, where only the non-enzymatic component is produced, and exponential growth with only enzym...

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The lysosome plays an important role in maintaining cellular nutrient homeostasis. Regulation of nutrient storage can occur by the ubiquitination of certain transporters that are then sorted into the lysosome lumen for degradation. To better understand the underlying mechanism of this process, we performed genetic screens to identify components of the sorting machinery required for vacuole memb...

Growth factors provide permission signals that allow mammalian cells to grow, proliferate and survive. One mechanism by which growth factors maintain this control is through the regulation of cell surface nutrient transporter expression. Following growth factor withdrawal, nutrient transporters are endocytosed and degraded in the lysosome, effectively terminating the cell's ability to obtain nu...

Systems biology has emerged as a critical concept for biological and medical research. Its growing recognition stems from the reality that organisms exist as systems, and the better we understand the interactions in these complex biological networks, the more readily we can develop effective prevention or treatment strategies that comprehensively address health problems. The field of systems bi...

We measured porewater profiles of inorganic (NH4 , NO − 3 (+NO − 2 ), PO 3− 4 (hereafter referred to as DIP)) and organic (DON, DOP) nutrients in seagrass-vegetated sediments at two sites in a shallow bay in Bermuda within close proximity (200 m) but subject to different nutrient loading. At both sites, total dissolved and inorganic nutrient concentrations were usually 1–2 orders of magnitude h...