Neuroimaging studies have indicated abnormalities in cortico-striatal-thalamo-cortical circuits in patients with obsessive-compulsive disorder compared with controls. However, there are inconsistencies between studies regarding the exact set of brain structures involved and the direction of anatomical and functional changes. These inconsistencies may reflect the differential impact of environme...

the obsessive beliefs questionnaire-44 (obq-44), a self-report measure, was developed by the obsessive compulsive cognitions working group (occwg) to assess beliefs considered relevant in the etiology and maintenance of obsessions and compulsions. the purpose of this study was to evaluate the psychometric properties of the persian language version of the obsessive beliefs questionnaire (pobq-44...

Obsessive compulsive symptoms are commonly reported in those with schizophrenia. Clozapine has previously been reported to induce, aggravate and alleviate these symptoms. It is unclear if these are similar to the symptoms experienced by those with obsessive compulsive disorder. This study describes the obsessive compulsive symptom profile of a population of patients with schizophrenia treated w...

The textbook description of comorbid depressive and obsessive compulsive disorders is that of onset of one following the onset or peak severity of the other, and recovery of one usually following recovery of the other. We describe a case who developed first onset obsessive compulsive disorder at tail of first onset major depression. This case highlights need for studies on the course of comorbi...

background: obsessive patients are distressed by intrusive thoughts, which are related to unreal threats. these patients feel that they are responsible for harming themselves and others. while controlling worry and meta-cognitive beliefs, the present study aimed at comparing the responsibility attitudes in obsessive compulsive patients with those in normal subjects to determine whether the diff...

BACKGROUND Prader Willi syndrome is a genetic disorder with a behavioural expression characterized by the presence of obsessive-compulsive phenomena ranging from elaborate obsessive eating behaviour to repetitive skin picking. Obsessive-compulsive disorder (OCD) has been recently associated with abnormal functional coupling between the frontal cortex and basal ganglia. We have tested the potent...

BACKGROUND There may be a link between anorexia nervosa and autism spectrum disorders. The aims of this study were to examine whether adolescents with anorexia nervosa have autism spectrum and/or obsessive-compulsive traits, how many would meet diagnostic criteria for autism spectrum disorder, and whether these traits are shared by parents. METHODS A total of 150 adolescents receiving outpati...

Acne is one of the most common dermatological diseases, and obsessive compulsive disorder is among the most frequent psychiatric conditions seen in dermatology clinics. Comorbidity of these conditions may therefore be expected. The aim of this study was to measure obsessive compulsive symptoms and quality of life in patients with acne vulgaris, compare them with those of healthy control subject...

Parents of autistic probands with high and low rates of repetitive behaviors were compared for rates of obsessive-compulsive traits and disorder. The rate of repetitive behaviors was assessed using the Autism Diagnostic Interview-Revised (ADI-R) in 176 autistic probands from 57 multiplex families. Obsessive-compulsive disorder (OCD) in parents was determined by direct interview using a parental...